RADIESSE® is a dermal filler injected into the skin using a fine needle to add volume, effectively smoothing facial wrinkles and folds, such as nasolabial folds—the lines extending from the nose to the corners of the mouth. Upon administration, RADIESSE® provides immediate improvement by restoring volume to the targeted areas. Over time, it stimulates the body’s natural collagen production, enhancing skin elasticity and structure for sustained aesthetic benefits. Your healthcare provider will administer the product to diminish the depth of wrinkles, resulting in a smoother and more youthful facial appearance.

How does the RADIESSE® product work?

Beyond its immediate effects, RADIESSE® distinguishes itself by promoting the production of collagen and elastin, essential proteins that maintain skin’s strength and elasticity. The CaHA microspheres act as a scaffold, stimulating fibroblasts to produce new collagen for up to a year and elastin for up to nine months following a single injection. This dual stimulation results in long-term improvements in skin quality, enhancing both structure and elasticity.

As the gel carrier is gradually absorbed, the newly formed collagen network remains, providing enduring support and contour to the treated areas. Over time, the CaHA microspheres are metabolized by the body’s natural processes, leaving behind the natural collagen matrix. This transition ensures that the aesthetic improvements are immediate and long-lasting, offering patients a rejuvenated and natural appearance.

RADIESSE® functions through a two-fold mechanism: it offers immediate volume enhancement to smooth wrinkles and folds while concurrently stimulating the body’s production of collagen and elastin. However, actual patients must consult their trusted medical professionals to ensure their suitability with RADIESSE dermal fillers and their safety throughout the treatment.

RADIESSE® Indications for Skin Treatments

​RADIESSE® is an FDA-approved dermal filler indicated for subdermal implantation to correct moderate to severe facial wrinkles and folds, such as nasolabial folds. Additionally, these products are approved for hand augmentation to address volume loss in the dorsum of the hands.

In clinical studies, RADIESSE® demonstrated higher viscosity and elasticity levels than hyaluronic acid-based fillers, providing the strength to lift and define while remaining at the injection site.

RADIESSE® Contraindications

​RADIESSE®, a dermal filler used for aesthetic enhancements, is contraindicated in individuals with severe allergies, including those with a history of anaphylaxis or multiple severe allergies, and in patients with known hypersensitivity to any of its components. Additionally, RADIESSE® is not recommended for patients with bleeding disorders.

For RADIESSE® (+), which contains lidocaine, contraindications extend to individuals with known hypersensitivity to lidocaine or similar anesthetics. Furthermore, RADIESSE® should not be used in patients with active skin inflammation or infection in or near the treatment area until the condition has been controlled.

It’s essential for aesthetic providers to understand the composition and packaging of RADIESSE fillers, ensuring patient safety for their cosmetic enhancements. They should also equip their customers with patient education, enabling them to make informed treatment decisions.

RADIESSE® Composition

RADIESSE® is a dermal filler composed of synthetic calcium hydroxylapatite (CaHA) microspheres—similar to minerals naturally found in human bones—suspended in a smooth, water-based gel carrier. This biocompatible and biodegradable formulation contains no animal- or human-derived components, which reduces the risk of allergic reactions and eliminates the need for pre-treatment allergy testing.

• The CaHA particles range in size from 25 to 45 microns and serve as a scaffold that supports the body’s natural collagen production, helping improve skin structure and elasticity over time. This makes RADIESSE® particularly effective in treating lower face volume loss and contouring areas such as the jawline and chin, offering natural-looking results that vary based on individual results, age, and skin condition.
• Because the components closely mimic substances found naturally in the body, RADIESSE® works in close harmony with the skin’s biology, delivering immediate and long-term aesthetic benefits.

RADIESSE® Packaging

​RADIESSE® dermal filler is supplied in a sterile, non-pyrogenic syringe, individually packaged within a sealed foil pouch to ensure product integrity. Each syringe is designed for single-use applications only and should not be resterilized or used if the packaging is compromised.

The standard packaging includes a pre-filled syringe containing 1.5 mL of RADIESSE®, accompanied by two 27-gauge thin-wall injection needles for precise administration. This meticulous packaging maintains the sterility and effectiveness of the product, ensuring safe and reliable treatment outcomes. ​

The comprehensive approach of ​RADIESSE® addresses the symptoms and underlying causes of skin aging, resulting in sustained and natural-looking aesthetic improvements for patients. It’s worth noting that proper administration of these products can ensure optimal outcomes.

Pre-Treatment

• Consult & Consent: Conduct a thorough consultation to determine the patient’s suitability for RADIESSE®, discuss benefits, risks, and aftercare, and obtain informed consent.
• Realistic Expectations: Set expectations based on individual results, considering factors like age and treatment area.
• Optional Anesthesia: To enhance comfort, apply a topical anesthetic 30–45 minutes before treatment. Providers may also use RADIESSE (+) for the indicated purposes.
• Disinfection: To reduce the risk of infection, disinfect the target area, such as the jawline or lower face.
• Marking (Optional): Mark precise injection sites to ensure accurate filler placement and optimal aesthetic outcomes.
• Potential Side Effects: Temporary redness, swelling, bruising, tenderness, and injection site irregularities can occur. These are mostly mild and transient and can resolve within a few days to a week. However, it’s important to discuss potential risks and benefits with the patient before proceeding.

RADIESSE® Injection Session

• Needle Selection: Use sterile needles of appropriate size and length for the targeted area and injection depth, as specified in the RADIESSE® product instructions.​
• Injection Techniques:
  • Linear Retrograde: Administer the filler by inserting the needle along wrinkle lines and injecting while withdrawing, effectively correcting wrinkles and restoring volume.​
  • Serial Puncture: Perform multiple small injections in a grid pattern to stimulate broader tissue areas and enhance volumization.​
• Injection Depth: As outlined in the product guidelines, inject RADIESSE® into the mid- to deep dermis, carefully avoiding the superficial dermis and blood vessels.​
• Injection Volume: Adjust the amount of RADIESSE® based on the patient’s anatomy, desired correction, and product characteristics. Begin with a conservative volume and incrementally increase to achieve optimal results.​

Post-Treatment

• Cooling: Apply a cool compress to the treated area for 10–15 minutes to minimize swelling and discomfort.​

• Massage (Optional): Gently massaging the treated area, as instructed by your healthcare provider, may help distribute the RADIESSE® dermal filler evenly and reduce swelling.​

• Results: While initial improvements may be visible immediately, optimal results typically develop over 4–6 weeks as RADIESSE® stimulates collagen production.

• Treatment Frequency: The number of treatments required varies based on individual factors, including age, facial anatomy, and desired outcomes. Your healthcare provider will determine the appropriate treatment plan tailored to your needs.

• Touch-Up Treatments: Additional touch-up sessions may be necessary to achieve and maintain the desired aesthetic results.

Important Note: This information is for educational purposes only. Always refer to the official RADIESSE® product instructions and manufacturer recommendations for the most up-to-date and detailed information on the injection protocol, safety data, and potential side effects.

Where to Shop for Radiesse Skin Fillers

​Med Supply Solutions provides a streamlined process for purchasing RADIESSE®, a leading dermal filler renowned for its effectiveness in treating facial wrinkles and volume loss. By visiting our official website, you can easily order the 3ml syringe of RADIESSE®.

While RADIESSE® is not available in a 5ml syringe, Med Supply Solutions offers a variety of other dermal fillers and aesthetic supplies to meet diverse treatment needs. Exploring our product range allows you to find fillers suitable for various applications, including facial wrinkle correction and volume restoration. Additionally, the platform provides detailed information on each product, aiding you in making informed decisions tailored to your aesthetic practice.