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PhilArt Products – Eye, Hair, Next

David Fuller

Last Updated On: June 24, 2025

Polynucleotides, naturally occurring DNA fragments, are gaining popularity in regenerative aesthetics. A 2024 systematic review of nine studies involving 219 patients found significant improvements in skin hydration, elasticity, and overall texture. These treatments stimulate fibroblast activity, creating an environment conducive to collagen production, and aid in cell repair and reducing inflammation, making them promising solutions for aging and damaged skin.

One notable brand incorporating this science is PhilArt, a line of aesthetic products developed by Croma Pharma. PhilArt specializes in formulations designed to target delicate areas like the eyes and scalp, aiming to restore skin and hair vitality at the cellular level. By utilizing polynucleotide technology, these treatments provide effective rejuvenation without the downtime typically associated with more invasive procedures.

In this article, we’ll explore the full range of PhilArt products, including their mechanisms, treatment protocols, and what you can expect from therapies targeting the eye area, hair, and upcoming innovations in regenerative aesthetics.

Key Takeaways

  • PhilArt is a polynucleotide-based biostimulator designed to rejuvenate the face, neck, and body by stimulating fibroblast activity and boosting collagen and elastin production.
  • The core PhilArt formulation is available in a 10 mg/mL concentration (20 mg/2 mL), ideal for improving skin tone, elasticity, and hydration without adding bulk or stiffness.
  • PhilArt Eye targets under-eye bags, fine lines, dark circles, and early eyelid ptosis, with treatments administered via microdroplets or linear threading.
  • For hair treatments, PhilArt Hair promotes scalp health by improving blood flow, stimulating fibroblast activity, and supporting hair follicle regeneration. These help alleviate hair thinning, telogen effluvium, and androgenetic alopecia.
  • PhilArt Next, now available, combines polynucleotides with non-crosslinked hyaluronic acid/mannitol for deeper tissue regeneration, addressing wrinkles, scars, and striae.
  • The PhilArt protocol involves a series of treatments spaced over several weeks, with maintenance sessions usually scheduled every 3–6 months.
  • The PhilArt line offers safe, effective, and non-invasive rejuvenation solutions for the face, neck, body, and scalp, making it a preferred option for patients seeking gradual, natural-looking improvements.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Croma PhilArt Fillers online, contact our sales department for more information.  

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CROMA PhilArt NEXT

Hyaluronic acid

Polynucleotides

$119.00

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PhilArt (Face/Neck/Body) Overview

The core PhilArt product is a biostimulator made of polynucleotides at a concentration of 10 mg/mL (20 mg/2 mL). It is designed to revitalize the face, neck, and body areas that show early signs of aging. Unlike volumizing fillers, PhilArt works by stimulating fibroblast activity, enhancing collagen and elastin production, and improving the skin’s overall structure.

PhilArt improves skin quality without adding bulk or stiffness, making it ideal for dull skin, early wrinkles, acne scars, and skin laxity. Injections are administered intradermally or subdermally in multiple sessions spaced 2–3 weeks apart. Results generally begin to appear after the second session, with gradual improvements through subsequent treatments.

Key Applications of PhilArt

  • Facial Rejuvenation: Ideal for softening fine lines, enhancing cheek structure, smoothing nasolabial folds, and refining the jawline. PhilArt improves skin tone and elasticity, resulting in a refreshed and youthful appearance without adding volume.
  • Neck Firming and Décolletage Smoothing: Targets early creases and skin laxity in these delicate areas, boosting collagen and hydration. The result is smoother, firmer skin in the neck and décolletage region.
  • Body Contour Support: Particularly effective for areas like the inner arms, abdomen, and above the knees, where early signs of skin thinning or texture loss appear. Regular treatments can improve skin density and reduce the appearance of crepey or sagging skin.

PhilArt Eye: Indications & Protocols

A doctor in a white coat holds a penlight and examines the eyes of a woman with curly hair wearing a green top, against a plain white background.

PhilArt Eye addresses common concerns in the periorbital region, such as under-eye bags, fine lines, and dark circles. The high-purity polynucleotides stimulate fibroblast activity, supporting collagen and elastin regeneration. Additionally, PhilArt Eye has anti-inflammatory properties that reduce puffiness, support skin hydration, and promote improved microcirculation, making it perfect for revitalizing tired-looking eyes.

Protocols for PhilArt Eye

  • Injection Method: Use a 30–32G needle or a micro-cannula for precision with minimal trauma. The choice of method depends on the patient’s anatomy and the injector’s preference.
  • Technique: Apply the product through superficial microdroplets or linear threading, placed just beneath the dermis. This ensures even distribution while minimizing the risk of vascular compromise in this sensitive area.
  • Session Frequency: Most patients require 2–3 sessions, spaced 3 weeks apart. This schedule allows for tissue recovery and ongoing biostimulation.
  • Timeline of Results: Visible results, including skin brightening and smoothing, can occur after the first session. Improvements peak after the third treatment, with continued remodeling over the following weeks.

PhilArt Hair: Scalp Rejuvenation Insights

A man with a beard and blue shirt examines his hairline in the mirror, using both hands to pull back his hair and look closely at his scalp.

PhilArt Hair targets mild to moderate hair thinning, including telogen effluvium and androgenetic alopecia in both men and women. It enhances the scalp environment by stimulating fibroblast activity, improving blood flow, and supporting collagen and elastin production.

Each vial of PhilArt Hair contains 15 mg/2 mL of purified polynucleotides, and treatment is administered intradermally using a microdroplet or fan technique. The product is distributed evenly across the scalp to rejuvenate hair follicles and improve overall scalp health.

Standard Protocol for PhilArt Hair Treatments

  • Initial Phase: Begin with one session per week for four consecutive weeks. This allows for consistent stimulation of the scalp, enhancing fibroblast activity and promoting follicular regeneration.
  • Follow-up Sessions: After the initial phase, sessions are spaced 2–3 weeks apart for another 1–2 months. This tapering schedule helps maintain the regenerative momentum while allowing the scalp to respond to therapy.
  • Maintenance Phase: Once the patient achieves the desired results, they can get maintenance treatments every 3–6 months. However, this depends on their individual hair cycles and concurrent therapies.

Patients often report improved scalp hydration, reduced shedding, and the growth of baby hairs within 6–12 weeks. For visual results, prospective patients can look for PhilArt Hair before and after so they know what to expect from this treatment.

This can also complement treatments like PRP, microneedling, or post-hair transplant care, enhancing graft survival and healing.

PhilArt Next & Pipeline: Future Applications

PhilArt Next is the newest addition to Croma Pharma’s bio-revitalization portfolio, featuring enhanced formulations designed for deeper tissue regeneration. This includes a hybrid combination of polynucleotides and non-crosslinked hyaluronic acid/mannitol at 10 mg/mL to tackle deeper wrinkles, scars, and striae.

Croma Pharma is also exploring innovations such as customizable PN chain-lengths, dosing formats, and accelerated protocols to streamline clinical workflows. These advancements will provide clinicians with greater flexibility while improving patient satisfaction.

As the global shift toward regenerative and non-invasive solutions continues, PhilArt is well-positioned to lead in biostimulatory skin therapies. With PhilArt Next already available, the brand is pushing the boundaries of skin rejuvenation, preparing to meet the evolving needs of both clinicians and patients.

Conclusion

PhilArt products are revolutionizing the field of regenerative aesthetics, offering natural-looking improvements through bio-revitalization rather than artificial volume. From the delicate under-eye areas to the scalp, these polynucleotide-based formulations enhance skin tone, texture, and elasticity.

The versatility and safety of PhilArt make it a preferred choice among clinicians and patients alike. With continued product development and the launch of PhilArt Next, the brand is poised to redefine non-surgical rejuvenation across the face, body, and hair.

FAQs

1. What are polynucleotides in PhilArt?

Polynucleotides (PNs) are DNA fragments that come from salmon sperm cells. They help regenerate skin by boosting collagen, repairing tissue, and reducing inflammation.

2. Is PhilArt Eye safe for all skin types?

Yes, PhilArt Eye has high biocompatibility and a good safety profile. However, practitioners still recommend patch testing for patients who are very sensitive or those with fish allergies.

3. How soon can I see results with PhilArt Hair?

Initial scalp improvements (less shedding, improved hydration) may be visible after 3–4 sessions. For significant density improvements, the treatment requires a commitment of 2–3 months.

4. Can practitioners combine PhilArt products with other treatments?

Yes, PhilArt integrates well with PRP, microneedling, HA fillers, and laser procedures. This multi-modal approach enhances results and long-term skin quality.

References

Webb WR, Rahman E, Rao P, et al. Points to ponder on the role of polynucleotides in regenerative and aesthetic medicine: a systematic review. Eur J Plast Surg. 2024;47(1):66. doi:10.1007/s00238-024-02209-x.

Lampridou S, Bassett S, Cavallini M, Christopoulos G. The Effectiveness of Polynucleotides in Esthetic Medicine: A Systematic Review. J Cosmet Dermatol. 2025;24(2):e16721. doi:10.1111/jocd.16721

Croma-Pharma introduces its newest injectable polynucleotide, PhilArt. Aesthetic Medicine. https://aestheticmed.co.uk/croma-pharma-introduces-its-newest-injectable

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