PERFECTHA® DEEP

Perfectha® results can last up to 18 months in areas such as cheekbones or the chin. For dynamic areas such as the lips, results tend to last approximately 6 months. The period of time between Perfectha® treatments will vary depending on the product used, treatment area(s), and individual differences. Your physician will also have their own preferred timeline, post-procedure, where they can assess your treatment results over time to determine the optimal time to ‘top-up’ different treatment areas, for the best results.

PERFECTHA® is a line of resorbable hyaluronic acid (HA) gel implants intended for reconstructive purposes in the treatment of facial lipoatrophy, morphological asymmetry associated with aging, or other underlying conditions. It is for intra-dermal and subcutaneous application to fill skin depressions and augment tissue volume. PERFECTHA® DEEP is specifically indicated for filling deep lines and depressions such as nasolabial folds and marionette lines. Perfectha® is also indicated for moderate contouring and volumization in areas such as cheekbones, chin, jawline, temples, nose, sub-orbicularis oculi fat (SOOF), and for lip augmentation.

Perfectha® Deep is a cross-linked hyaluronic acid gel dermal filler, formulated to treat deep facial lines and skin depressions. In addition, this formulation can be used to increase lip volume, redefine the nose, and treat nasolabial folds and marionette lines. With a cross-linking rate of 90%, the Perfectha® gel is injected into the deep dermis. Suitable for filling deep wrinkles through injection in the medium to deep dermis.

1. Before starting Perfectha® treatment, the healthcare professional must obtain information about the patient's history and state of health.
2. Assemble the syringe ready for injection:
   1. Holding the syringe upright on the ribbed part of the Luer lock, tilt the white cap to break seals (Fig 1).
   2. Remove the syringe cap in a straight upward direction (Fig 2).
   3. Unscrew cap from the needle/ cannula casing. Holding the Luer Lock firmly in a fixed position, screw the desired needle/ cannula into the Luer lock of the syringe by rotating the needle/ cannula (Fig 3).
   4. Remove needle/ cannula casing.
3. Before starting the Perfectha® injection, expel all the air from the needle/ cannula by pushing on the plunger until a drop of gel appears at the tip of the needle/ cannula.
4. The patient should be seated at an angle of at least 45° in order to prevent the face from becoming distorted, which increases the risk of "imprecise treatment".
5. Marking the area to be treated should help guarantee the precision of the Perfectha® injection. The area to be treated should first be cleaned and disinfected with an appropriate antiseptic solution. Local or regional anesthetic block may be used depending on patient/ healthcare Professional preference.
6. The quantity to be injected depends on the area to be corrected. Do not inject more than 3.0ml per treatment site during each session.
7. Inject the Perfectha® product slowly; injection of one 1ml syringe takes between 4 to 5 minutes. A low injection speed may help to prevent the detachment of accessories during injection and to reduce the occurrence of local adverse events after injection.
8. If the needle/ cannula becomes blocked, do not increase the pressure on the plunger rod; stop the injection and replace the needle/ cannula. A bubble in the syringe barrel does not constitute a known risk during administration.
9. Perfectha® administration must be halted just before withdrawing the needle/ cannula in order to prevent spillage of the product at the administration site.
10. As the results are immediate, the quantity administered must correct the defect without producing over-correction.
11. The treated area should be massaged gently to ensure the implant is well distributed.
12. Application of ice packs to the treated area for several minutes is recommended in order to minimize swelling.
13. Dispose of syringe and needle/ cannula as contaminated clinical waste.

Contraindications:

• Do not mix Perfectha® with other products before injection.
• Do not inject into the periorbital region or glabella region.
• Avoid intramuscular or intravascular injections.
• Do not over-correct.
• Avoid injections in patients with known hypersensitivities to avian proteins, feathers, and egg products.
• Do not use Perfectha® in patients with certain medical conditions or hypersensitivities.
• Do not use Perfectha® on areas previously treated with fillers of animal origin, permanent implants, or implants containing a substance other than hyaluronic acid.

After-care

Dosage:

Limit per session: No more than 30ml per 60kg of body-weight for each treatment session, without using anesthesia beforehand.
Yearly limit: The total amount used in a year shouldn't exceed 60ml per 60kg of body-weight.

• Makeup: Avoid applying makeup for 24 hours after injection.
• Sun protection: Limit exposure to strong sunlight for 2-3 weeks after treatment.
• Cold and heat: Avoid extreme cold (below 0°C) and saunas/steam baths for 2-3 weeks after injection.

Caution:

Sensitive areas: Injections in the nose and lips require extra care due to the higher risk of side effects in these delicate areas.