The actual duration of effects is highly dependent upon the lifestyle and physiology of the patient. However, it has been noted that it can last for 3 to 6 months after injection.
Start with an injection of 1.25-2.5 units (0.05-0.1 mL at each location) into the inner and outer parts of the upper eyelid’s orbicularis oculi muscle, as well as into the outer part of the lower eyelid’s orbicularis oculi muscle. The maximum initial dose should be 25 units per eye, and the total dosage should not exceed 100 units every three months.