Crespine Gel is usually applied by an experienced medical practitioner (an orthopedic surgeon or a specialist sports physician) by injection directly into the joint-line of the affected joint. The use of imaging techniques has been shown to be quality promoting.

• To maintain the healthy condition of the joint cartilage tissue as long as possible.
• Time-saving effect for the patient with only one appointment for the treatment.
• A single injection intervention enhances security for the patient.
• The regenerating of pain-relieved joint tissue functioning.

Crespine Gel Plus is an injectable orthopaedic filler designed to alleviate osteoarthritis symptoms such as pain and inflammation. It contains 14mg/mL of cross-linked hyaluronic acid, 1mg/mL of non-crosslinked hyaluronic acid, and 3mg/mL of prilocaine as active ingredients. The two forms of hyaluronic acid work together to lubricate and enhance mobility in areas like the knees and hips by decreasing friction. Prilocaine ensures the injection process is painless. The product is made by BioPolymer, a firm that specializes in producing medical devices. This synthetic gel is sterile, viscoelastic, biocompatible, absorbable, and devoid of endotoxins and animal-derived components. Each Crespine Gel Plus package includes one pre-filled 2mL syringe, four traceability labels, and an information leaflet. It should be stored in a clean area, away from extreme heat or cold (between 2℃ and 25℃).

• Crespine Gel is injected by an experienced medical practitioner directly into the joint-line interstices.
• The stabilized hyaluronic acid arrives directly in the joint-line where the pain has its origin, covering the cartilage protectively to prevent further degeneration by abrasion.
• The single injection should be repeated at regular intervals, with an early stage medical clarification of joint pain helping to benefit from the Crespine Gel effect for a more pleasant lifespan with an original natural joint.
• Pay extra attention to the affected joints during treatment and do not inject the filler in joints with active infections or inflammation as this could worsen the side effects.

Contraindications

• The safety of this implant in young people below 18 years of age, pregnant people, and people who are breastfeeding has not been determined.
• Additionally, certain people must steer clear from this hyaluronic acid-based implant due to heightened risk of hypersensitivity.

After-care

• Depending on the diagnosis and the location of the osteoarthritis, it can be reasonable to integrate more activity in everyday life as soon as the pain in the joint begins to be relieved.
• Immediately after the intervention, no exaggerated exercise or sporting activities should be undertaken. However, normal day-to-day mobility is directly possible.
• The cartilage will be encouraged to regenerate after the treatment by restarting mobility with a healthy amount of activity.
• A strengthening of the ambient joint muscle tissue will effect additional collateral support.
• Physio-, Ergo- or physical –therapies can also represent additional countermeasures when the pain relief in the joint is initiated by Crespine Gel and more mobility is attractive to the patient.
• Healthy nutrition is also an additional factor for the regeneration of the joint tissue.