Thymosin Beta 4 (TB500) (5 mg) is a synthetic version of a naturally occurring peptide found in many cell types. It consists of a 43-amino acid sequence and has a molecular weight of approximately 4963 g/mol. This peptide is supplied as a high-purity lyophilized powder in a 5 mg vial, suitable for controlled laboratory use.

In Thymosin Beta 4 research, the peptide has been studied for its role in cellular migration, cytoskeletal organization, and tissue-related processes. Its structure allows researchers to explore how peptides interact with cellular environments under controlled experimental conditions.

Thymosin Beta 4 (TB500) (5mg) Key Features & Specs

• Subcategory: Healing & Regenerative Peptides
• Strength: 5mg
• CAS: 77591-33-4
• Chemical Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
• Molecular Weight: 4963 g/mol
• Peptide Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Ile-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH
• Synonyms: Timbetasin

For laboratory research use only.

Thymosin Beta 4 (TB500) (5mg) Research Uses

Thymosin Beta 4 (TB500) is being studied for its involvement in cellular processes related to tissue organization, structural protein interactions, and wound healing. Research often focuses on how the peptide influences cell movement, angiogenesis, and tissue dynamics.

The peptide is also under investigation for its role in cellular signaling, particularly in contexts where coordinated cellular responses and structural adaptations are observed.

Thymosin Beta 4 (TB500) (5mg) Insights & Observed Findings

Research on the TB500 peptide has focused on its behavior in controlled environments, particularly regarding cell migration and interactions with structural proteins. Varying concentrations of TB500 have been evaluated depending on the study design and biological models.

While these observations provide insights into the peptide’s effects on cellular dynamics, they remain limited to research settings and do not reflect clinical outcomes.

Thymosin Beta 4 (TB500) (5mg) Handling & Storage

• Store at –20°C in a controlled laboratory environment.
• Protect from light, heat, and moisture to maintain peptide integrity.
• Allow the vial to reach room temperature before opening to reduce condensation.
• Once reconstituted, store the solution at 2–8°C for short-term use.
• Avoid repeated freeze-thaw cycles.
• Aliquot to minimize repeated freeze-thaw cycles and ensure consistency.
• Follow appropriate laboratory protocols for preparation and handling.

Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

1. Malinda KM, Sidhu GS, Mani H, et al. Thymosin beta4 accelerates wound healing. J Invest Dermatol. 1999;113(3):364-368. doi:10.1046/j.1523-1747.1999.00708.x
2. Shrivastava S, Srivastava D, Olson EN, DiMaio JM, Bock-Marquette I. Thymosin beta4 and cardiac repair. Ann N Y Acad Sci. 2010;1194:87-96. doi:10.1111/j.1749-6632.2010.05468.x
3. Smart N, Risebro CA, Melville AA, et al. Thymosin beta4 induces adult epicardial progenitor mobilization and neovascularization. Nature. 2007;445(7124):177-182. doi:10.1038/nature05383
4. Kleinman HK, Sosne G. Thymosin β4 Promotes Dermal Healing. Vitam Horm. 2016;102:251-275. doi:10.1016/bs.vh.2016.04.005