SS-31 is a synthetic mitochondria-targeting peptide analog designed for laboratory research on cellular energy systems and oxidative stress pathways. Its compact tetrapeptide structure enables studies of...
SS-31 is a synthetic mitochondria-targeting peptide analog designed for laboratory research on cellular energy systems and oxidative stress pathways. Its compact tetrapeptide structure enables studies of mitochondrial membrane interactions and cellular bioenergetics under experimental conditions.
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SS-31 (30mg), also known as MTP-131 or Elamipretide, is a synthetic peptide composed of modified amino acids engineered to selectively target mitochondrial membranes. Its sequence, D-Arg-dimethyl-Tyr-Lys-Phe-NH₂, contributes to its stability and affinity for lipid-rich environments within cells.
With a chemical formula of C₃₂H₄₉N₉O₅ and a molecular weight of 639.8 g/mol, SS-31 is characterized by its small size and its ability to target cellular models. It has been studied for its role in mitochondrial processes, particularly those involving oxidative stress, membrane integrity, and energy production.
The peptide is typically supplied as a lyophilized powder in a research-grade vial, with purity commonly verified by HPLC and mass spectrometry, ensuring reproducibility in laboratory studies.
For laboratory research use only.
SS-31 (30mg) is being researched for its interaction with mitochondrial membranes and cellular energy systems. In laboratory models, it has been studied for its potential to influence bioenergetic efficiency and oxidative balance.
Research often focuses on cellular environments in which mitochondrial function is critical, including studies of energy metabolism, stress responses, and membrane stabilization. The peptide is also being investigated in models examining cellular responses to reactive oxygen species and metabolic strain.
Its ability to localize within mitochondria makes it a key subject in research exploring cellular resilience and energy regulation under experimental conditions.
Preclinical studies of SS-31 have examined its activity under various experimental conditions, including in vitro assays and animal models. Dosing in these studies is often reported as micrograms per kilogram (µg/kg) or at controlled concentrations in cell cultures.
Observed findings suggest that SS-31 may modulate mitochondrial membrane dynamics and cellular energy pathways, particularly under induced stress. These results depend on the model systems and experimental parameters used.
Laboratory research also indicates that small mitochondrial peptides such as SS-31 may show rapid cellular uptake and targeted localization, supporting their use in mechanistic studies of mitochondrial function.
SS-31 (30mg) should be stored under controlled laboratory conditions to maintain structural stability. Recommended storage includes refrigeration at 2–8 °C, with –20 °C suitable for extended storage when necessary.
The lyophilized peptide should be kept away from light, moisture, and excessive heat. After reconstitution using an appropriate sterile laboratory solvent, solutions are generally maintained at 2–8 °C and handled using standard laboratory procedures.
To preserve peptide integrity, avoid repeated freeze–thaw cycles. Proper personal protective equipment should be used during handling, and disposal must follow institutional biosafety protocols.
Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
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