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SS-31 15mg

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SS-31 15mg

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This peptide will be available soon.

Quantity Discount (%) Price
1 - 5 — $78.00
6 - 10 — $777.00
11 - 20 2.56 % $76.00
21+ 3.85 % $75.00

Why choose Novera Compounds peptides

Research-grade Quality

Every compound is manufactured to research-grade standards and intended strictly for laboratory and research use. Consistent quality you can build a reproducible protocol around.

Documented and traceable

  • Batch number on every vial

  • Published Certificates of Analysis

  • Purity verified by third-party testing

Handled and shipped with care

Temperature-sensitive compounds are stored and shipped under controlled conditions, so material arrives in the state your research requires. Expert support on hand at every step.

About the product

SS-31 (15mg), also known in scientific literature as Elamipretide or MTP-131, is a synthetic tetrapeptide developed for laboratory research. It consists of four modified amino acids arranged in the sequence D-Arg-dimethyl-Tyr-Lys-Phe-NH₂.

This SS-31 mitochondrial peptide is typically produced by solid-phase peptide synthesis (SPPS) and purified to high purity, commonly verified by HPLC and mass spectrometry. Supplied as a lyophilized powder in a sealed vial, SS-31 (15mg) has been studied for its interaction with mitochondrial membranes and its role in cellular energy-related research.

SS-31 (15mg) Key Features & Specs

  • Subcategory: Longevity & Anti-Aging Peptides
  • Strength: 14mg
  • CAS: 736992-21-5
  • Chemical Formula: C₃₂H₄₉N₉O₅
  • Molecular Weight: 639.8 g/mol
  • Peptide Sequence: D-Arg-dimethyl-Tyr-Lys-Phe-NH2
  • Synonyms: MTP-131, Elamipretide

For laboratory research use only.

SS-31 (15mg) Research Uses

SS-31 (15mg) is being investigated for its role in mitochondrial function and cellular energy metabolism. In laboratory models, it has been studied for its potential association with mitochondrial membranes and its influence on oxidative balance.

SS-31 research often focuses on energy-demanding tissues, including cardiac and skeletal muscle models, as well as broader investigations into metabolic activity and age-related cellular changes. These studies aim to better understand how mitochondrial-targeting peptides may support cellular function under controlled experimental conditions.

SS-31 (15mg) Insights & Observed Findings

In vitro studies involving the SS-31 peptide commonly explore activity within nanomolar to micromolar concentration ranges, depending on the experimental design. In animal models, dosing has been evaluated in microgram-per-kilogram (µg/kg) ranges to assess mitochondrial-related outcomes.

Observations in controlled settings have included changes in markers associated with cellular energy production and oxidative stress. These Elamipretide peptide research findings are preliminary and will guide further investigation into mitochondrial interactions and cellular response mechanisms.

SS-31 (15mg) Handling & Storage

  • Recommended storage: 2–8 °C; –20 °C where applicable.
  • Protection: Keep the lyophilized peptide protected from light, heat, and moisture prior to reconstitution.
  • Reconstitution: Reconstitute using sterile laboratory-grade solvents.
  • Handling: Handle with appropriate aseptic techniques.
  • Post-reconstitution storage: Maintain the solution under refrigerated conditions (2–8 °C).
  • Freeze-thaw cycles: Avoid repeated freeze-thaw cycles.
  • Protocols: Follow institutional laboratory protocols for additional handling guidance.

Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

  1. PubChem CID 11764719. National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/Elamipretide
  2. Elamipretide: Uses, interactions, mechanism of action. DrugBank. https://go.drugbank.com/drugs/DB11981
  3. Birk AV, Liu S, Soong Y, et al. The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. J Am Soc Nephrol. 2013;24(8):1250-1261. doi:10.1681/ASN.2012121216
  4. Tse BC, Dvoriantchikova G, Tao W, et al. Mitochondrial targeted therapy with elamipretide (MTP-131) as an adjunct to tumor necrosis factor inhibition for traumatic optic neuropathy in the acute setting. Exp Eye Res. 2020;199:108178. doi:10.1016/j.exer.2020.108178
  5. Brown DA, Hale SL, Baines CP, et al. Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther. 2014;19(1):121-132. doi:10.1177/1074248413508003
  6. Li M, Kong D, Meng L, Wang Z, Bai Z, Wu G. Discovery of novel SS-31 (d-Arg-dimethylTyr-Lys-Phe-NH2) derivatives as potent agents to ameliorate inflammation and increase mitochondrial ATP synthesis. RSC Adv. 2024;14(41):29789-29799. Published 2024 Sep 18. doi:10.1039/d4ra05517a