NOVERA COMPOUNDS

SS-31 10mg

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SS-31 10mg

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Quantity Discount (%) Price
1 - 5 — $45.00
6 - 10 8.89 % $41.00
11 - 20 17.78 % $37.00
21+ 24.44 % $34.00

Why choose Novera Compounds peptides

Research-grade Quality

Every compound is manufactured to research-grade standards and intended strictly for laboratory and research use. Consistent quality you can build a reproducible protocol around.

Documented and traceable

  • Batch number on every vial

  • Published Certificates of Analysis

  • Purity verified by third-party testing

Handled and shipped with care

Temperature-sensitive compounds are stored and shipped under controlled conditions, so material arrives in the state your research requires. Expert support on hand at every step.

About the product

SS-31 peptide, also known as Elamipretide or MTP-131 in research literature, is a laboratory-developed tetrapeptide designed for mitochondrial-focused investigations. It is synthesized using controlled peptide assembly techniques and undergoes rigorous purification and analytical verification to ensure consistency across research.

This compound is frequently used in experimental models examining mitochondrial integrity and energy-related processes, particularly in studies evaluating how targeted peptides may influence cellular responses to oxidative stress and metabolic demand.

SS-31 (10mg) Key Features & Specs

  • Subcategory: Longevity & Anti-Aging Peptides
  • Strength: 14mg
  • CAS: 736992-21-5
  • Chemical Formula: C₃₂H₄₉N₉O₅
  • Molecular Weight:  639.8 g/mol
  • Peptide Sequence: D-Arg-dimethyl-Tyr-Lys-Phe-NH2
  • Synonyms: MTP-131, Elamipretide

For laboratory research use only.

SS-31 (10mg) Research Uses

SS-31 (10mg) is being researched for its role in mitochondrial-related processes and cellular energy regulation. In laboratory settings, it has been examined in models that explore how peptides may influence mitochondrial stability and signaling.

Studies often include metabolic research, oxidative stress models, and investigations involving energy-demanding tissues, such as cardiac and skeletal muscle. These applications aim to expand the understanding of how mitochondrial-targeting compounds function under controlled experimental conditions.

SS-31 (10mg) Insights & Observed Findings

In vitro research involving SS-31 (10mg) typically evaluates activity across nanomolar to micromolar concentration ranges, depending on the study design. In animal models, dosing has been explored in microgram-per-kilogram (µg/kg) ranges to assess mitochondrial-related responses.

Observations have included changes in cellular energy markers and oxidative balance under controlled conditions. These findings are investigational and serve as a foundation for further study into mitochondrial interactions and cellular response patterns.

SS-31 (10mg) Handling & Storage

Store SS-31 (10mg) under frozen conditions at approximately –20°C in a controlled laboratory environment. Keep the lyophilized material protected from light, moisture, and temperature fluctuations prior to use.

Reconstitute using sterile laboratory-grade solvents and handle with appropriate aseptic technique. After reconstitution, maintain refrigerated conditions and avoid repeated freeze-thaw cycles to preserve sample integrity.

Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

  1. PubChem CID 11764719. National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/Elamipretide
  2. Elamipretide: Uses, interactions, mechanism of action. DrugBank. https://go.drugbank.com/drugs/DB11981
  3. Birk AV, Liu S, Soong Y, et al. The mitochondrial-targeted compound SS-31 re-energizes ischemic mitochondria by interacting with cardiolipin. J Am Soc Nephrol. 2013;24(8):1250-1261. doi:10.1681/ASN.2012121216
  4. Tse BC, Dvoriantchikova G, Tao W, et al. Mitochondrial targeted therapy with elamipretide (MTP-131) as an adjunct to tumor necrosis factor inhibition for traumatic optic neuropathy in the acute setting. Exp Eye Res. 2020;199:108178. doi:10.1016/j.exer.2020.108178
  5. Brown DA, Hale SL, Baines CP, et al. Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther. 2014;19(1):121-132. doi:10.1177/1074248413508003
  6. Li M, Kong D, Meng L, Wang Z, Bai Z, Wu G. Discovery of novel SS-31 (d-Arg-dimethylTyr-Lys-Phe-NH2) derivatives as potent agents to ameliorate inflammation and increase mitochondrial ATP synthesis. RSC Adv. 2024;14(41):29789-29799. Published 2024 Sep 18. doi:10.1039/d4ra05517a