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PT-141 5mg

PT-141 is a synthetic melanocortin peptide analog derived from α-melanocyte-stimulating hormone (α-MSH) and is studied for its role in neuroendocrine signaling pathways. Laboratory models have investigated...

PT-141 is a synthetic melanocortin peptide analog derived from α-melanocyte-stimulating hormone (α-MSH) and is studied for its role in neuroendocrine signaling pathways. Laboratory models have investigated its effects on central nervous system signaling, melanocortin receptor activity, and cellular communication processes. Supplied as a lyophilized powder in a sealed research-grade vial, it is manufactured to high purity and undergoes analytical testing for controlled experimental use.

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PT-141 5mg

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Quantity Discount (%) Price
1 - 5 — $39.00
6 - 10 7.69 % $36.00
11 - 20 15.38 % $33.00
21+ 23.08 % $30.00

Why choose Novera Compounds peptides

Research-grade Quality

Every compound is manufactured to research-grade standards and intended strictly for laboratory and research use. Consistent quality you can build a reproducible protocol around.

Documented and traceable

  • Batch number on every vial

  • Published Certificates of Analysis

  • Purity verified by third-party testing

Handled and shipped with care

Temperature-sensitive compounds are stored and shipped under controlled conditions, so material arrives in the state your research requires. Expert support on hand at every step.

About the product

PT-141 (5mg) is a synthetic cyclic peptide belonging to the melanocortin peptide family. It is structurally derived from alpha-melanocyte-stimulating hormone (α-MSH) and contains modified amino acids to enhance its stability under experimental conditions. This peptide is commonly studied for its interaction with melanocortin-related signaling systems.

PT-141 has been investigated in laboratory settings focused on neuroendocrine communication and central signaling pathways.

PT-141 (5mg) Key Features & Specs

PT-141 (5mg) is prepared for use in controlled laboratory environments to ensure accurate peptide characterization and consistent experimental results. It is frequently included in research exploring how melanocortin peptides influence cellular signaling and communication pathways.

  • Subcategory: Neuroendocrine & Melanocortin Research Peptides
  • Strength: 5 mg
  • CAS Number: 189691-06-3
  • Chemical Formula: C₅₀H₆₈N₁₄O₁₀
  • Molecular Weight: 1025.182 g/mol
  • Peptide Sequence: Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)
  • Synonyms: PT141

For laboratory research use only.

PT-141 (5mg) Research Uses

PT-141 (5mg) has been investigated within laboratory environments focused on neuroendocrine signaling and melanocortin pathways. As a melanocortin peptide analog, it serves as a tool for exploring how peptide signaling influences communication within the central nervous system.

Research involving this peptide typically examines biological systems related to hormonal signaling, neuronal communication, and central regulatory pathways. These studies aim to understand the mechanisms by which melanocortin peptides interact with cellular systems that govern neuroendocrine function.

In experimental models, PT-141 is used to investigate how signaling molecules modulate cellular pathways involved in central signaling and peptide-mediated communication.

PT-141 (5mg) Insights & Observed Findings

Preclinical and in vitro studies involving melanocortin peptides such as PT-141 have evaluated activity across nanomolar concentration ranges, depending on the biological system and experimental design. These studies are conducted to assess peptide-mediated signaling responses.

Animal studies investigating melanocortin signaling have reported dosing ranges in the microgram per kilogram (µg/kg) scale. Experimental parameters may vary depending on the pathways and systems being studied.

Observed findings suggest that melanocortin-related peptides may influence molecular pathways involved in neuroendocrine signaling, cellular communication, and central regulatory processes. These findings remain under investigation and should not be interpreted as evidence of clinical outcomes.

PT-141 (5mg) Handling & Storage

  • Store lyophilized powder at 2–8 °C or –20 °C in a controlled environment, protected from light, heat, and moisture.
  • After reconstitution with sterile laboratory-grade solvent, store solution refrigerated (2–8°C).
  • Avoid repeated freeze-thaw cycles. Use aseptic technique and follow institutional biosafety guidelines.

Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

  1. National Center for Biotechnology Information. PubChem Compound Summary for CID 9941379, Bremelanotide. https://pubchem.ncbi.nlm.nih.gov/compound/Bremelanotide
  2. Molinoff PB, Shadiack AM, Earle D, Diamond LE, Quon CY. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003;994:96-102. doi:10.1111/j.1749-6632.2003.tb03167.x
  3. Wessells H, Blevins JE, Vanderah TW. Melanocortinergic control of penile erection. Peptides. 2005;26(10):1972-1977. doi:10.1016/j.peptides.2004.11.035
  4. Rosen RC, Diamond LE, Earle DC, Shadiack AM, Molinoff PB. Evaluation of the safety, pharmacokinetics and pharmacodynamic effects of subcutaneously administered PT-141, a melanocortin receptor agonist, in healthy male subjects and in patients with an inadequate response to Viagra. Int J Impot Res. 2004;16(2):135-142. doi:10.1038/sj.ijir.3901200