Kisspeptin-10 (10mg) is a synthetic decapeptide derived from the KISS1 gene. It represents a shorter biologically active fragment within the kisspeptin family. Composed of a 10-amino-acid sequence, Kisspeptin-10 is closely associated with the metastin peptide group. It has a molecular weight of approximately 1302.4 g/mol and is typically supplied as a lyophilized powder in a sterile vial for laboratory preparation.
In research settings, Kisspeptin-10 is produced to high purity standards suitable for controlled experimental use. The peptide has been studied for its role in signaling pathways involved in hormonal regulation and neuroendocrine communication, with a focus on reproductive system signaling and broader cellular communication processes.
Kisspeptin-10 (10mg) Key Features & Specs
- Subcategory: Sexual Health & Hormonal Peptides
- Strength: 10mg per vial
- CAS: 374675-21-5
- Chemical Formula: C₆₃H₈₃N₁₇O₁₄
- Molecular Weight:4 g/mol
- Peptide Sequence: Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
- Synonyms: Kisspeptin-10, Metastin (45-54), KP-10
For laboratory research use only.
Kisspeptin-10 (10mg) Research Uses
Research on Kisspeptin-10 has focused on its role in endocrine signaling and the regulation of the reproductive system. It has been studied for its interaction with hormonal pathways that influence gonadotropin release and reproductive axis activity.
Additionally, Kisspeptin research explores its role in the onset of puberty, fertility-related signaling, and neuroendocrine communication. The peptide is also being investigated for its broader effects on cellular signaling and regulatory feedback systems throughout the body.
Kisspeptin-10 (10mg) Insights & Observed Findings
In preclinical and in vitro studies, Kisspeptin-10 has been evaluated across varying concentration ranges depending on the experimental model. Observations suggest dose-dependent activity in hormone-related signaling environments.
Studies have used Kisspeptin-10 under controlled conditions to examine the effects of pulsatile and sustained exposure on endocrine markers. These findings remain within experimental contexts and aim to improve understanding of peptide-driven signaling mechanisms, rather than establishing clinical applications.
Kisspeptin-10 (10mg) Handling & Storage
- Store lyophilized powder at –20°C in a controlled environment, protected from light and moisture.
- After reconstitution with sterile laboratory-grade solvent, store solution refrigerated (2–8°C).
- Avoid repeated freeze-thaw cycles. Use aseptic technique and follow institutional biosafety guidelines.
Compliance Notice (paste as-is, no heading needed): This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Kotani M, Detheux M, Vandenbogaerde A, et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem. 2001;276(37):34631-34636. doi:10.1074/jbc.M104847200
- Oakley AE, Clifton DK, Steiner RA. Kisspeptin signaling in the brain. Endocr Rev. 2009;30(6):713-743. doi:10.1210/er.2009-0005
- Sliwowska JH, Woods NE, Alzahrani AR, Paspali E, Tate RJ, Ferro VA. Kisspeptin a potential therapeutic target in treatment of both metabolic and reproductive dysfunction. J Diabetes. 2024;16(4):e13541. doi:10.1111/1753-0407.13541
- Mills EGA, Dhillo WS, Comninos AN. Kisspeptin and the control of emotions, mood and reproductive behaviour. Journal of Endocrinology. 2018;239(1):R1-R12. doi:10.1530/joe-18-0269