Gonadorelin (10mg) is a synthetic version of the naturally occurring peptide gonadotropin-releasing hormone (GnRH), a key regulator of endocrine signaling within the hypothalamic–pituitary axis. This peptide, consisting of 10 amino acids, plays a central role in coordinating hormone signaling pathways in biological systems.
Gonadorelin is commonly studied in laboratory settings investigating endocrine signaling, reproductive hormone regulation, and neuroendocrine communication.
Gonadorelin (10mg) Key Features & Specs
- Subcategory: Hormonal & Endocrine Research Peptides
- Strength: 10 mg
- CAS: 9034-40-6
- Chemical Formula: C₅₅H₇₅N₁₇O₁₃
- Molecular Weight:3 g/mol
- Peptide Sequence: Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly
- Synonyms: GnRH, LHRH, LH-RH, Gonadotropin-Releasing Hormone, Luteinizing Hormone-Releasing Hormone, Gonadoliberin, Factrel
For laboratory research use only.
Gonadorelin (10mg) Research Uses
Gonadorelin has been studied in laboratory environments focused on endocrine signaling and reproductive hormone regulation. As a synthetic GnRH analog, it is commonly used in research models investigating communication between the hypothalamus and the pituitary gland.
Research involving this peptide often examines biological systems related to hormone secretion, reproductive system signaling, and neuroendocrine regulation. These studies aim to better understand how peptide signaling contributes to the coordination of hormone release and feedback mechanisms within endocrine networks.
In experimental models, Gonadorelin is used to investigate how signaling molecules influence cellular communication pathways involved in hormonal balance and physiological regulation.
Gonadorelin (10mg) Insights & Observed Findings
Preclinical and in vitro studies involving GnRH analogs such as Gonadorelin have evaluated peptide activity across nanomolar to micromolar concentration ranges, depending on the biological system being studied. These models are often used to evaluate hormone signaling dynamics and cellular responses.
Animal studies investigating endocrine signaling peptides have reported experimental dosing in the microgram-per-kilogram (µg/kg) range. Experimental conditions vary depending on the interaction between peptide systems and the biological pathways under investigation.
Observed findings suggest that GnRH-related peptides may influence molecular pathways involved in hormone signaling and endocrine communication. These findings are part of ongoing research and should not be interpreted as clinical outcomes.
Gonadorelin (10mg) Handling & Storage
- Store under controlled laboratory conditions
- Refrigeration at 2–8 °C is recommended; –20 °C may be used for storage as appropriate
- Protect the lyophilized powder from light, heat, and moisture
- After reconstitution using sterile laboratory-grade solvent, store the solution at 2–8 °C and handle according to standard laboratory protocols
- Avoid repeated freeze–thaw cycles, as these may affect peptide stability
- Use appropriate laboratory protective equipment during handling and follow institutional biosafety guidelines for safe handling and disposal
Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.
References
- Flanagan CA, Manilall A. Gonadotropin-Releasing hormone (GNRH) receptor structure and GNRH binding. Frontiers in Endocrinology. 2017;8:274. doi:10.3389/fendo.2017.00274
- Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. Gonadotropin-Releasing hormone receptors. Endocrine Reviews. 2004;25(2):235-275. doi:10.1210/er.2003-0002
- Casati L, Ciceri S, Maggi R, Bottai D. Physiological and pharmacological overview of the gonadotropin releasing hormone. Biochemical Pharmacology. 2023;212:115553. doi:10.1016/j.bcp.2023.115553