Synvisc One Pros and Cons – All About the Treatment

David Fuller

Last Updated On: October 3, 2024

Osteoarthritis is a common degenerative joint disease that affects millions worldwide. It causes significant pain and reduced mobility. According to the Centers for Disease Control and Prevention (CDC), about 33 million adults in the U.S. suffer from osteoarthritis.

Synvisc One, a viscosupplementation treatment, aims to alleviate the pain and stiffness associated with osteoarthritis by injecting hyaluronan directly into the knee joint. This single-injection treatment mimics the natural synovial fluid in joints, providing lubrication and cushioning to ease movement and reduce discomfort.

In this article, we will explore Synvisc One’s pros and cons, delving into its effectiveness, potential side effects, and patient experiences to help you make an informed decision.

Key Takeaways

• Synvisc One provides effective pain relief and improved joint function for many patients with knee osteoarthritis.
• Unlike traditional treatments that require multiple injections, Synvisc One is administered as a single dose, simplifying the treatment process.
• Common side effects include localized swelling, pain, and stiffness, which are generally temporary but can be bothersome.
• Although uncommon, there is a risk of severe adverse reactions, such as infections or allergic responses, necessitating prompt medical attention.
• The treatment’s effectiveness can vary between individuals, with some patients experiencing limited or no benefit, which may require exploring alternative options.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Synvisc online, contact our sales department for more information.

What is Synvisc One?

Synvisc One is an injectable treatment designed to alleviate knee pain caused by osteoarthritis. The active ingredient is hylan G-F 20, a gel-like substance that mimics the natural synovial fluid in the knee. By enhancing lubrication and cushioning within the joint, Synvisc One improves mobility and reduces pain.

Approved by the US Food and Drug Administration (FDA) in 2009, Synvisc One has a strong safety profile backed by extensive clinical research. It is administered as a single injection, providing long-lasting relief, typically up to six months. The treatment’s convenience and efficacy make it a popular choice for managing knee osteoarthritis symptoms.

Pros of Synvisc One

• Convenience of a Single Injection: Synvisc One requires only one injection, offering a convenient solution for busy individuals or those living far from their clinic. This single shot provides long-lasting pain relief, eliminating the need for multiple doctor visits, saving time and reducing travel costs. The “one and done” approach simplifies treatment schedules and enhances patient convenience.
• Long-Lasting Pain Relief: Synvisc One provides pain relief for up to six months with just one injection. This reduces the need for frequent doctor visits and allows patients to engage in daily activities with ease and less discomfort. Comparatively, Synvisc One is often praised for its long-lasting effects, offering up to half a year of knee pain relief.
• Improved Joint Mobility and Function: Patients using Synvisc One often experience enhanced joint movement, making it easier to walk, climb stairs, and perform daily tasks. The gel-like substance lubricates and cushions the joint, reducing pain and allowing for smoother motion. This treatment significantly improves joint function, offering relief from the limitations imposed by knee pain.

Cons of Synvisc One

While this treatment brings many benefits, it’s also key to note the downsides, like possible Synvisc side effects and the fact that not everyone may get the same relief from pain.

• Potential Side Effects: Synvisc One may cause side effects such as pain, swelling, and fluid build-up in the knee. Itching, warmth, and redness at the injection site are also possible. Some people might experience dizziness or headaches. Rare but serious reactions include breathing problems or face swelling, requiring immediate medical attention. 
• Cost Considerations: Synvisc One can be expensive, and not all insurance plans cover it, leading to out-of-pocket expenses. Checking insurance coverage beforehand is advisable. The high cost of Synvisc ingredients contributes to the treatment’s price. Exploring payment options or financial aid might help patients afford this valuable treatment without financial strain.
• Varying Patient Response and Efficacy: Synvisc One’s effectiveness varies among patients. Some experience significant knee pain relief and improved mobility, while others see less benefit. Factors like overall health, knee condition severity, and previous treatments influence outcomes. 

Clinical Data and Patient Testimonials

Evaluating Synvisc One’s efficacy and safety involves analyzing clinical trial data. This method gives medical professionals a clear basis for understanding Synvisc One’s effectiveness and safety. The following table summarizes key findings from various clinical trials, focusing on pain relief, joint mobility, and side effect occurrence outcomes.

Clinical Trial	Key Findings	Efficacy Results	Safety Observations
Multicenter Randomized Study	Compared single injection Synvisc One with placebo	Significantly reduced pain scores at 26 weeks	Minor side effects, similar to placebo
Extended Evaluation Study	Long-term efficacy and safety over 1 year	Pain relief sustained over 52 weeks	Low incidence of serious adverse events
Comparative Effectiveness Trial	Assessed against other hyaluronic acid injections	Comparable or better improvement in joint function	Similar safety profile to other HA products

Real-life Experiences and Testimonials

Patients often share their experiences with Synvisc One, highlighting both the upsides and challenges. These stories can offer a unique perspective on the treatment’s effects.

1. Anonymous: “I received one shot of Synvisc-one in both knees. The treatment worked well, with no issues. My knees felt better. The treatment wore off about six months later, so I went in for another treatment about seven months after the first. I had the treatment in both knees. Two days later, my knees started swelling, and four days later, my knees were locked into place; I could not bend at all.“
2. Honda Mike: “At 56 years old, I run 8 miles daily and 26 on Saturday. My knees hurt and I thought I would never run again. Three runners on my team had this injection and said it works. I had it 8 years ago. Immediate relief and still today I run pain free.”
3. Jason: “Having lost a quarter-shaped size of cartilage in my right knee, so bone on bone in that one and in the left knee advanced osteo, which hurts more than the right, I know about pain. Synvisc is the best!..”

Making an Informed Decision

Choosing Synvisc One involves careful thought. Talk with a doctor and think about what you need and want.

• Weighing the Pros and Cons: Evaluating Synvisc One involves weighing its benefits and drawbacks. It offers a convenient single injection for lasting pain relief and improved joint function, appealing to those with joint issues. However, potential side effects, costs, and varying results must be considered. 
• Consultation with a Healthcare Professional: Consulting a healthcare professional is essential before deciding on Synvisc One. They assess the treatment’s pros and cons, ensuring it aligns with your health history and goals. A thorough evaluation of past treatments, current health issues, and potential side effects helps create a tailored plan. This informed discussion provides insights into expected relief and costs, aiding confident decision-making about care.
• Considering Individual Needs and Preferences: Responses to Synvisc One vary based on personal health conditions. Some experience significant improvements in pain and flexibility, while others may not notice substantial changes. It’s crucial to consider individual health history, current status, and reactions to previous treatments. 

Conclusion

Synvisc One provides long-lasting pain relief and improved joint function with a single injection. However, potential side effects and cost may be concerns, and results can vary. Consulting a healthcare professional can help determine if Synvisc One aligns with your needs and preferences.

FAQs

1. What is Synvisc One treatment? 

Synvisc One is a medical treatment for managing knee osteoarthritis pain.

2. What are the benefits of using Synvisc One? 

Synvisc One provides long-term pain relief, improves mobility, and enhances overall quality of life.

3. Are there any drawbacks associated with Synvisc One treatment? 

Potential drawbacks include side effects such as swelling or fluid build-up around the knee.

4. Should the pros and cons be considered before starting Synvisc One treatment? 

It’s essential to discuss the pros and cons with your healthcare provider to make an informed decision.

References

Centers for Disease Control and Prevention Osteoarthritis. Published January 26, 2024. https://www.cdc.gov/arthritis/osteoarthritis/index.html

In Y, Ha CW. A Multicenter, Randomized, Double-Blinded, Parallel-Group, Placebo-Controlled Phase I/IIa Study to Evaluate the Efficacy and Safety of a Single Intra-Articular Injection of YYD302 in Patients with Knee Osteoarthritis. Journal of Clinical Medicine. 2022;11(6):1482. doi:https://doi.org/10.3390/jcm11061482