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David Fuller
Last Updated On: May 6, 2025
A 2020 clinical study revealed that poly-L-lactic acid (PLLA) fillers can significantly improve skin elasticity, texture, and volume, with results lasting up to two years—far outpacing traditional hyaluronic acid fillers. Their collagen-stimulating power has made them a rising star in regenerative aesthetics.
Two of the most prominent PLLA-based treatments are Lanluma and Sculptra. Both are celebrated for their gradual, natural-looking effects, offering volumizing benefits for the face, body, and buttocks. Yet despite sharing the same base ingredient, they differ in formulation, indications, and user experience.
In this article, we’ll compare Lanluma vs Sculptra—breaking down their composition, application areas, results, and clinical nuances to help you make a confident, informed choice.
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Both Lanluma and Sculptra utilize poly-L-lactic acid (PLLA) to stimulate the body’s natural collagen production. However, their formulations and reconstitution methods differ, which can influence their suitability depending on the area of treatment and practitioner preference.
These preparation differences can impact injection techniques, treatment durations, and patient outcomes.
The choice between Lanluma and Sculptra depends on the patient’s aesthetic goals and the specific area targeted for treatment.
Lanluma is ideal for those looking for comprehensive rejuvenation, especially when targeting larger treatment zones or combining face and body contouring in a single treatment plan.
Both Lanluma and Sculptra produce gradual, natural-looking results through collagen stimulation, but they differ slightly in onset and visibility of outcomes.
The effectiveness and longevity of both treatments can vary based on patient age, skin condition, lifestyle habits, and treatment adherence.
When evaluating a PLLA filler, cost-effectiveness often plays a key role—especially for patients considering treatment across multiple or larger body areas. Below is a simplified comparison:
Aspect | Lanluma | Sculptra |
Cost Per Vial | $1,250–$1,500 | $800–$1,200 |
Typical Sessions Required | 1–3 sessions | 2–4 sessions |
Vial Size Options | Two sizes (Lanluma V and Lanluma X) for facial and body areas | Standard vial size for facial treatments only |
Best For | Large-volume therapies (e.g., buttocks, thighs, hip dips) | Targeted facial volume restoration |
Overall Value | More cost-effective for body contouring due to fewer sessions and vial flexibility | It may be more cost-efficient for smaller, facial-only treatments |
Lanluma’s flexible dosing and broad treatment scope often translate into better value for patients pursuing full-body enhancement, whereas Sculptra may be more suited for facial-specific concerns.
Lanluma and Sculptra are both effective PLLA-based fillers, offering gradual, natural-looking results through collagen stimulation. While they share the same core ingredient, Lanluma stands out for its versatility in both facial and body treatments—particularly for patients seeking volume in areas like the buttocks, thighs, and hip dips. Its flexible vial sizes and fewer required sessions often make it the more cost-effective option for full-body contouring.
Sculptra, in contrast, remains a gold standard for facial rejuvenation. Patients often choose Sculptra to address volume loss in the cheeks, temples, and nasolabial folds, achieving subtle enhancements over time.
Ultimately, both options provide long-lasting improvements, and choosing the right one depends on individual goals, treatment areas, and consultation with an experienced aesthetic provider.
Practitioners use Lanluma for both face and body treatments, while they primarily use Sculptra to restore facial volume.
Both offer results lasting up to two years, with individual longevity varying based on factors like metabolism and lifestyle.
Lanluma typically requires fewer sessions (1–3), whereas Sculptra often involves 2–4 sessions over several months.
Lanluma may be more cost-effective for larger treatment areas due to its vial sizes and fewer sessions needed.
Haddad A, Avelar L, Fabi SG, et al. Injectable poly-L-lactic acid for body aesthetic treatments: an international consensus on evidence assessment and practical recommendations. Aesthetic Plast Surg. 2024;1-11. https://link.springer.com/article/10.1007/s00266-024-04499-9
Signori R, Barbosa ADP, Cezar-dos-Santos F, et al. Efficacy and safety of poly-L-lactic acid in facial aesthetics: a systematic review. Polymers. 2024;16(18):2564. https://www.mdpi.com/2073-4360/16/18/2564
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