How Does Aqualyx Work?

Last Updated On: April 30, 2025

Fat cell breakdown, also known as adipocytolysis or lipolysis, has been a major focus in the development of non-surgical body contouring treatments. Research has shown that deoxycholic acid—an agent known to trigger adipocytolysis—can effectively destroy fat cells when injected into the subcutaneous layer, resulting in a visible reduction in fat volume.

One product that leverages this mechanism is Aqualyx. Designed for targeted fat reduction, Aqualyx uses a modified form of deoxycholic acid to break down stubborn fat pockets. Its minimally invasive nature has made it a popular alternative to traditional liposuction.

In this article, we’ll take a closer look at how Aqualyx works, exploring its key ingredients, mechanism of action, and what patients can expect before, during, and after treatment.

Key Takeaways

• Aqualyx works through adipocytolysis, using deoxycholic acid to break down and eliminate fat cells in targeted areas without surgery.
• The treatment remains localized at the injection site, minimizing systemic effects and allowing for safe, natural fat removal through the body’s metabolic processes.
• Aqualyx focuses on refining small, stubborn fat pockets, making it ideal for areas like the chin, abdomen, thighs, flanks, and upper arms.
• Most patients require two to four sessions spaced a few weeks apart, with full visible results developing over six to eight weeks.
• Aqualyx can work best if a professional combines it with a broader wellness plan that includes healthy eating, exercise, and, where appropriate, complementary treatments like RF skin tightening.
• Its minimally invasive nature and quick recovery time make it a popular alternative to traditional liposuction for those seeking targeted body contouring.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. Contact our sales department for more information about buying Aqualyx online.

Mechanism of Action: Adipocytolysis

The core mechanism behind Aqualyx is adipocytolysis—the targeted destruction of fat cells. The treatment’s active ingredient, deoxycholic acid, is a bile acid naturally found in the human digestive system, where its primary role is to emulsify dietary fats for easier absorption.

When Aqualyx targets subcutaneous fat, deoxycholic acid begins to work in several steps:

• It disrupts the phospholipid bilayer of adipocytes (fat cells), compromising their integrity.
• It induces cell lysis, causing the fat cells to break apart.
• It triggers a local inflammatory response, recruiting macrophages (a type of immune cell) to clean up the destroyed fat cell debris.
• It releases triglycerides, which are gradually metabolized and eliminated through the lymphatic system.

This gradual breakdown process is confined to the treated area without damaging nearby tissues, ensuring precision and safety. This highly targeted approach is a key reason for Aqualyx’s growing popularity in non-surgical body contouring.

Pharmacokinetics and Metabolism

After injection, Aqualyx remains localized at the treatment site, significantly reducing the risk of systemic absorption. The triglycerides released from destroyed fat cells follow the body’s natural metabolic pathways:

• They are first converted into free fatty acids in the liver.
• These fatty acids are then either transported for energy use or excreted through normal metabolic processes.

Because the body’s natural systems handle the disposal of fat breakdown products safely, the procedure does not require anesthesia or surgical incisions.

Most patients are able to return to normal activities within 24 to 48 hours, with only minor swelling, bruising, or tenderness expected during the short recovery period.

Clinical Outcomes and Efficacy

Aqualyx’s indications and uses focus on localized fat reduction, not overall weight loss. It is highly effective for targeting small, stubborn fat pockets that persist despite proper diet and exercise.

Common treatment areas include:

• Chin (submental fat)
• Abdomen
• Thighs
• Flanks
• Upper arms
• Back and bra bulges

Typically, patients require two to four sessions spaced about three to six weeks apart, depending on the size of the treatment area and the individual’s goals.

Visible improvements usually appear after the second session, with full results becoming evident around six to eight weeks post-treatment. Each treatment session further enhances the fat reduction effect, resulting in a gradual, natural-looking improvement.

Integration into Treatment Plans

Aqualyx works best in individuals already close to their ideal body weight but struggle with isolated fat deposits that resist traditional methods. It is most effective when integrated into a comprehensive wellness and aesthetic plan.

Professionals typically follow a structured approach:

• Assessment: Carefully measure fat thickness and assess skin elasticity to ensure suitability.
• Customization: Adjust the volume of Aqualyx injected and the number of sessions based on the specific area and the patient’s aesthetic goals.
• Combination: Aqualyx often works with complementary treatments like radiofrequency (RF) skin tightening or muscle toning therapies to further enhance contouring results.
• Aftercare: Patients should rest briefly, use cold compresses to reduce swelling, maintain good hydration, and gently mobilize the treated area to support optimal lymphatic drainage.

To preserve results long-term, maintaining a balanced diet and regular exercise routine remains crucial. Aqualyx can deliver remarkable improvements, but patient lifestyle still plays a key role in sustaining the outcome.

Conclusion

Aqualyx works by using the body’s natural chemistry—specifically deoxycholic acid—to safely break down and eliminate fat cells. This non-surgical treatment is both safe and clinically proven, making it an increasingly popular tool in aesthetic medicine for those seeking to contour and refine targeted areas.

Whether you’re looking to refine your jawline or slim your waistline, Aqualyx offers a clinically backed solution with minimal downtime and a natural-looking finish.

FAQs

1. How does Aqualyx break down fat cells?

Aqualyx contains deoxycholic acid, which disrupts the membranes of fat cells, causing them to break down. The body then metabolizes and excretes the contents naturally.

2. Is Aqualyx safe for everyone?

No. Aqualyx is not recommended for pregnant or breastfeeding individuals, those with autoimmune conditions, or those with severe liver disease. Always consult a qualified practitioner.

3. When will I see results from Aqualyx?

Most patients begin to see results after the second session, with full results visible 6 to 8 weeks after the final treatment. Patience is key, as the body gradually eliminates fat.

4. Can I combine Aqualyx with other treatments?

Yes. Depending on your goals and practitioner’s recommendation, they may combine Aqualyx with other aesthetic treatments, such as radiofrequency skin tightening or facial fillers.

5. Are the results of Aqualyx permanent?

Yes, Aqualyx permanently destroys the treated fat cells. However, maintaining a healthy lifestyle is necessary to prevent new fat from accumulating.

6. What are the common side effects?

Swelling, redness, tenderness, and mild bruising at the injection site are common and usually resolve within a few days.

7. Is the procedure painful?

Most patients experience mild discomfort, but local anesthetic or numbing cream is often used to minimize pain.

8. How many sessions are needed?

Typically, 2–4 sessions spaced 3–4 weeks apart are needed, but this varies by area and individual response.

References

Widgerow AD, Kilmer SL, Garruto JA, Stevens WG. Non-surgical fat reduction and topical modulation of adipose tissue physiology. J Drugs Dermatol. 2019;18(4):375-380.

Mlosek RK, Skrzypek E, Migda B, Migda M, Woźniak W. The efficacy of high-frequency ultrasound-guided injection lipolysis in reducing fat deposits located on the inside of the knees. J Ultrason. 2021;20(83):e273-e278. doi:10.15557/JoU.2020.0048