NOVERA COMPOUNDS

MOTs-C 10mg

MOTs-C is a synthetic mitochondria-derived 16-amino-acid peptide studied for its role in cellular energy regulation and metabolic signaling pathways. Laboratory models investigate its effects on mitochondrial...

MOTs-C is a synthetic mitochondria-derived 16-amino-acid peptide studied for its role in cellular energy regulation and metabolic signaling pathways. Laboratory models investigate its effects on mitochondrial communication, metabolic adaptation, and cellular stress responses. Supplied as lyophilized powder in a sealed research-grade vial, it is manufactured to high purity via analytical testing for controlled experimental use.

10% off, code: PEPTEN
Purity Guarantee

MOTs-C 10mg

Sign in to view pricing and purchase this product.

Log In Sign Up
Quantity Discount (%) Price
1 - 5 — $55.00
6 - 10 9.09 % $50.00
11 - 20 18.18 % $45.00
21+ 25.45 % $41.00

Why choose Novera Compounds peptides

Research-grade Quality

Every compound is manufactured to research-grade standards and intended strictly for laboratory and research use. Consistent quality you can build a reproducible protocol around.

Documented and traceable

  • Batch number on every vial

  • Published Certificates of Analysis

  • Purity verified by third-party testing

Handled and shipped with care

Temperature-sensitive compounds are stored and shipped under controlled conditions, so material arrives in the state your research requires. Expert support on hand at every step.

About the product

MOTs-C (10mg) is a synthetic peptide derived from a sequence encoded within mitochondrial DNA, classified as a mitochondria-derived peptide. It consists of 16 amino acids and has been studied in laboratory settings for its role in cellular signaling pathways involved in metabolism and energy homeostasis.

This peptide is involved in intracellular communication between mitochondria and other cellular compartments, making it a subject of interest in research on metabolic regulation and stress-response signaling.

MOTs-C (10mg) Key Features & Specs

  • Subcategory: Mitochondrial & Metabolic Research Peptides
  • Strength: 10 mg
  • Chemical Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂
  • Molecular Weight:64 g/mol
  • Peptide Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
  • Synonyms: Mitochondrial peptide, Mitochondria-derived peptide

For laboratory research use only.

MOTs-C (10mg) Research Uses

MOTs-C (10mg) has been studied in laboratory environments focused on metabolic regulation and mitochondrial signaling. As a mitochondria-derived peptide, it is commonly used in research exploring how intracellular signaling pathways coordinate energy balance and cellular responses to metabolic stress.

Studies involving this peptide often examine biological systems related to glucose metabolism, cellular energy homeostasis, and stress-response signaling pathways. These investigations aim to understand how mitochondrial peptides influence communication between organelles and the broader cellular environment.

In experimental models, MOTs-C is used to investigate how signaling molecules interact with cellular pathways involved in metabolic adaptation and mitochondrial function.

MOTs-C (10mg) Insights & Observed Findings

Preclinical and in vitro studies of mitochondria-derived peptides like MOTs-C have evaluated activity across nanomolar to micromolar concentration ranges, depending on the biological model and experimental design. These studies are conducted to assess cellular signaling responses under controlled conditions.

Animal studies investigating metabolic peptides have reported dosing ranges in the microgram per kilogram (µg/kg) scale. Experimental parameters may vary depending on the metabolic pathways and physiological systems being studied.

Observed findings suggest that MOTs-C-related signaling may influence molecular pathways involved in energy regulation, metabolic signaling, and cellular stress responses. These findings remain under investigation and should not be interpreted as evidence of clinical outcomes.

MOTs-C (10mg) Handling & Storage

  • Store lyophilized powder at 2–8 °C or –20 °C in a controlled environment, protected from light, heat, and moisture.
  • After reconstitution with sterile laboratory-grade solvent, store solution refrigerated (2–8°C).
  • Avoid repeated freeze-thaw cycles. Use aseptic technique and follow institutional biosafety guidelines.

Compliance Notice: This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.

References

  1. Reynolds JC, Lai RW, Woodhead JST, et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nature Communications. 2021;12(1). doi:10.1038/s41467-020-20790-0
  2. Zheng Y, Wei Z, Wang T. MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation. Frontiers in Endocrinology. 2023;14:1120533. doi:10.3389/fendo.2023.1120533
  3. Lee C, Zeng J, Drew BG, et al. The Mitochondrial-Derived Peptide MOTS-C promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism. 2015;21(3):443-454. doi:10.1016/j.cmet.2015.02.009
  4. Wan W, Zhang L, Lin Y, et al. Mitochondria-derived peptide MOTS-c: effects and mechanisms related to stress, metabolism and aging. Journal of Translational Medicine. 2023;21(1):36. doi:10.1186/s12967-023-03885-2