At 15 mg, patients have reached the maximum once-weekly dose in the tirzepatide prescribing schedule. No further escalation is available beyond this level, and patients established here may continue at 15 mg for as long as clinical response and tolerability support ongoing treatment. MOUNJARO® 15 mg KwikPen® is administered once weekly by subcutaneous injection, at any time of day, with or without food.
Injection sites are the abdomen, thigh, or — when another person administers the dose — the back of the upper arm. Sites should be rotated with each dose. For context, the full titration schedule begins at 2.5 mg once weekly for 4 weeks, then increases to 5 mg. If additional glycemic response is needed, the dose may be increased by 2.5 mg increments after at least 4 weeks on the current dose, up to this 15 mg maximum. Clinicians managing patients across the titration range may refer to other MOUNJARO® KwikPen® doses for full dose-range reference.
If a dose is missed, it may be administered within 4 days (96 hours) of the scheduled date. If more than 4 days have passed, skip the missed dose and resume the regular weekly schedule. When using MOUNJARO® with insulin, administer as separate injections and never mix. Both injections may be given in the same body region but not adjacent to each other.