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Latisse Active Ingredient – About Bimatoprost

David Fuller

Last Updated On: June 21, 2024

According to the American Academy of Opthalmology, bimatoprost emerged as a cornerstone ingredient, revolutionizing the quest for enhanced facial appearance. Though initially known for its therapeutic role in treating glaucoma, bimatoprost has become the focal point of attention for its exceptional cosmetic capabilities.

Latisse is a growth serum that leverages the power of bimatoprost to redefine lash and brow aesthetics. By capitalizing on bimatoprost’s unique properties, Latisse offers a transformative solution, prolonging the growth phase of lashes and brows to unveil a strikingly longer, darker, and denser appearance.

In this article, we delve into Latisse’s main ingredient, bimatoprost, and explore its various applications to unravel the allure of this serum.

Key Takeaways

  • Bimatoprost is the active ingredient in Latisse, a popular eyelash enhancement product.
  • It promotes eyelash growth by extending the growth phase of the eyelash hair cycle.
  • Bimatoprost has been proven effective and safe for enhancing eyelash length, thickness, and darkness.
  • Apart from its cosmetic use, bimatoprost is also utilized in the treatment of glaucoma and ocular hypertension.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Latisse online, contact our sales department for more information.

Pharmacological Properties of Bimatoprost

Bimatoprost, the active ingredient in Latisse, is a prostaglandin analog that promotes eyelash growth by extending the growth phase of eyelash hairs. After application to the upper eyelashes, bimatoprost absorbs into the skin, reaching hair follicles and stimulating growth. This process, known as pharmacokinetics, describes how the drug moves through the body.

Pharmacodynamics, or how bimatoprost interacts with the body, involves keeping eyelashes in their growth phase more prolonged than usual, resulting in longer, thicker, and darker lashes. Latisse’s formula, which includes benzalkonium chloride, sodium chloride, and water, ensures safety and efficacy.

Latisse users apply the serum with a special brush to their upper eyelid edges nightly. This routine promotes noticeable improvements for those with sparse lashes, enhancing overall eye appearance. Its FDA approval assures users of its safety and effectiveness. The combined action of bimatoprost’s absorption and interaction with eyelash follicles provides a scientifically backed method for achieving fuller, more prominent lashes.

Clinical Efficacy of Bimatoprost for Eyelash Enhancement

Bimatoprost clinical studies show improved eyelash growth. Results highlight its safety and effectiveness. Clinical studies on bimatoprost, the active ingredient in Latisse, have demonstrated its effectiveness in promoting eyelash growth. These studies involved individuals with inadequate or sparse eyelashes and showed that regular application of bimatoprost led to longer, thicker, and darker lashes.

In clinical trials, it effectively promoted eyelash growth. However, some adverse reactions include eye pruritus, conjunctival hyperemia, and skin hyperpigmentation. Concurrent use with other intraocular pressure-lowering prostaglandin analogs should be monitored closely. 

Additionally, permanent iris pigmentation may occur. Studies in Korean women, Japanese patients, and pediatric populations4 have evaluated its safety and efficacy. Overall, Latisse has shown positive results in enhancing eyelash appearance while being well-tolerated.

Medical Applications of Bimatoprost

Bimatoprost is used to treat glaucoma and manage ocular hypertension. It also has potential uses in other eye conditions. 

  • Glaucoma Treatment: Bimatoprost lowers eye pressure in glaucoma and other eye diseases. It can help prevent blindness and nerve damage. It should be used under healthcare professional supervision as a prescription medication. Bimatoprost has medical applications beyond cosmetic use, effectively managing ocular hypertension and treating glaucoma.
  • Ocular Hypertension Management: Bimatoprost is commonly prescribed to lower intraocular pressure and manage ocular hypertension, reducing the risk of glaucoma development or preventing further damage in diagnosed patients. Healthcare professionals should educate patients about its proper usage and potential side effects during consultations for comprehensive care.
  • Other Potential Uses in Ophthalmology: Bimatoprost has potential uses, treating hypotrichosis of the eyebrows, glaucoma, and ocular surface diseases. Research suggests it may also promote corneal wound healing. 

Considerations for Patient Discussions

Medical professionals must provide clear and detailed information when counseling patients on Latisse use. Counseling patients on applying and using Latisse is crucial for achieving positive outcomes. Here are the key points to consider:

  • Explain that Latisse extends the growth phase of eyelashes, promoting longer, thicker, and darker lashes over time.
  • Emphasize applying Latisse only to the base of the upper eyelashes with the provided brush once daily.
  • Discuss potential side effects, such as itching, redness, or darkening of the skin around the eyes. Professionals should also explain cases of Latisse orbital fat loss so patients can manage their expectations.
  • Stress the importance of using Latisse as prescribed and not exceeding the recommended dosage.
  • Advise on what to do if a dose is missed or the solution accidentally gets into the eyes.
  • Inform patients that visible results may take several weeks and require patience.
  • Advise seeking medical attention for any concerning symptoms or adverse reactions.
  • Address any questions or concerns to ensure patients clearly understand Latisse before starting.
  • Emphasize regular follow-up appointments to monitor progress and address any issues.
  • Encourage open communication for guidance and support throughout the Latisse treatment journey.

Addressing Safety Concerns and Contraindications

Latisse, containing bimatoprost, comes with specific safety concerns and contraindications that should be carefully considered when prescribing the product. Below are essential points to discuss with patients:

  • Patients with pre-existing eye conditions should use Latisse cautiously under medical supervision.
  • Individuals with a history of macular edema or ocular inflammation should avoid using Latisse because it can worsen these conditions.
  • Latisse may cause darkening of the skin around the application area, which can be permanent in some cases.
  • Patients need to be aware that Latisse may potentially cause iris pigmentation changes when used directly into the eye to treat glaucoma.
  • Healthcare professionals must screen patients for a history of allergic reactions to any ingredients in Latisse before prescribing it.
  • Patients should be informed about rare but serious adverse effects such as orbital fat atrophy.
  • Women who are pregnant or planning pregnancy should avoid using Latisse until further research clarifies its safety in this population.
  • Counseling is necessary for individuals using other medications affecting intraocular pressure or having undergone ocular surgery to avoid complications.
  • Healthcare providers should emphasize accurate application and avoiding contact lens contamination during Latisse use to prevent adverse effects on vision and eye health.


Bimatoprost, the active ingredient in Latisse, has demonstrated efficacy and safety in promoting eyelash growth. Its pharmacological properties, mode of action, and clinical applications make it a valuable option for patients seeking to enhance the appearance of their eyelashes. Medical professionals should be well-informed about bimatoprost to engage in informed discussions with patients considering Latisse or other bimatoprost-containing products.


1. What’s in Latisse that makes it work?

Latisse contains an active ingredient called bimatoprost, which promotes longer and thicker lash and eyebrow growth.

2. Can I compare Latisse with GrandeLash? Are they similar?

Latisse and GrandeLash differ in their active ingredients; Latisse uses bimatoprost, while GrandeLash uses a different ingredient.

3. Are there any side effects I should watch out for with Latisse?

Potential side effects of Latisse include orbital fat loss and changes in eye color with long-term use. It should be used cautiously during pregnancy.

4. How often must I apply this lash serum for the best results?

Apply Latisse once daily on clean skin at bedtime for best results, and be patient for noticeable results.


What You Should Know About Eyelash Growth Serums. American Academy of Ophthalmology. Published December 5, 2019. https://www.aao.org/eye-health/tips-prevention/latisse

Kara D. Active Ingredient in Latisse May Grow More Than Eyelashes. Dr. Lee B. Daniel, Aesthetic Plastic Surgery. Published November 13, 2010. Accessed May 20, 2024. https://aestheticplasticsurg.org/active-ingredient-in-latisse-may-grow-more-than-eyelashes/



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