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Xeomin for Masseter: Understanding Jaw Slimming

David Fuller

Last Updated On: June 21, 2024

According to clinical data from a recent study, patients who received three Xeomin injections experienced a significant 43.12% reduction in masseter muscle volume afterward. This muscle, responsible for chewing, can become enlarged if overused.

Xeomin, a neuromodulator and muscle relaxant. It offers therapeutic and cosmetic benefits that help maintain the masseter muscle and facial aesthetics. With its proven efficacy and safety profile, Xeomin is a preferred option for facial rejuvenation over other available treatments.

This article delves into the anatomy of the masseter muscle, proper patient selection, and strategies for managing potential adverse effects.

Key Takeaways

  • Xeomin is a viable option for jaw slimming and facial contouring, offering a non-invasive approach to achieving desired aesthetic outcomes.
  • Understanding the anatomy of the masseter muscle and its role in facial aesthetics is crucial for determining the optimal dosage and administration techniques for Xeomin treatment.
  • Proper patient selection, dosage calculation, and injection techniques are essential for safe and effective Xeomin masseter treatments.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to order Xeomin online, contact our sales department for more information.

The Role of Xeomin in Jaw Slimming

Xeomin is highly effective in slimming the jawline by targeting the masseter muscle, causing it to relax and reduce in size. This treatment reshapes the face for a more defined appearance, offering both aesthetic and functional advantages without affecting normal functions like talking or eating.

Understanding the Masseter Muscle Anatomy

The masseter muscle in the cheek area is vital for jaw movement and chewing. Understanding its structure is essential for those considering Xeomin for jaw slimming. Xeomin targets the masseter muscle to achieve a slimmer jawline, reshaping the face without affecting normal functions. 

Injected Xeomin relaxes the masseter muscle, offering aesthetic and functional benefits, like easing facial pain or tense jaws. Xeomin injections provide a non-surgical option for jawline contouring and pain relief, targeting this powerful muscle for a more balanced facial appearance.

Dosage Calculation and Guidelines for Xeomin Masseter Treatment

Figuring out the right amount of Xeomin for jaw slimming requires careful planning—it’s all about getting the dose just right. Too much Xeomin can lead to unwanted side effects, while too little may not achieve the desired results. Therefore, proper dosing is crucial for successful and safe jawline contouring.

Determining the Optimal Xeomin Dosage for Masseter

Determining the right Xeomin dose for masseter treatment is crucial for jaw slimming. This involves a careful balance to achieve desired results while minimizing side effects.

  • The recommended Xeomin dose for masseter treatment is 20 Units per session for standardized treatment across patients.
  • Administer 20 Units as five 4-unit injections targeting specific areas for symmetry and effectiveness.
  • Adjust dosage based on the size and strength of the patient’s masseter muscle.
  • Review the patient’s history with botulinum toxin products to anticipate response to Xeomin.
  • Follow proper reconstitution practices to maintain Xeomin’s potency and efficacy.
  • Discuss patient goals to align expectations with treatment plans.
  • Check for contraindications, ensuring patient suitability for Xeomin treatments.
  • Monitor outcomes and adjust future doses based on results and potential side effects.

Injection Techniques and Administration Considerations

Injecting Xeomin into the masseter muscle requires skill and precision. This process is crucial for achieving jaw slimming without compromising safety.

  • Use Safe Techniques: Perform intramuscular injections at a 90-degree angle to reach the masseter muscle accurately.
  • Prepare the Patient: Have them sit up straight with their head slightly tilted back for better access.
  • Administer with Care: Gently insert the needle into each predefined site, avoiding nearby nerves and blood vessels.
  • Follow Post-treatment Instructions: Share Xeomin post-treatment instructions with patients to aid recovery and enhance outcomes.
  • Monitor for Side Effects: Look for adverse reactions following treatment, such as swelling or asymmetry.
  • Ensure Symmetry: Carefully assess both sides of the jawline after injections to confirm symmetrical results.

Patient Selection Criteria and Considerations for Xeomin Masseter Treatment

Patient selection is crucial for Xeomin in the masseter muscle. Doctors carefully evaluate potential candidates, considering who would benefit most and who should avoid treatment due to safety concerns. This ensures optimal outcomes and patient safety throughout the treatment process.

Assessing Patient Eligibility for Jaw Slimming with Xeomin

Choosing the right patients for jaw slimming with Xeomin is key. It ensures both safety and satisfaction. Here are the points to consider:

  • Check for Realistic Goals: Patients should want a slimmer jawline, not a complete change in face shape. They need to understand what Xeomin can do.
  • Health Status Matters: Check to ensure the patient has no history of reactions to botulinum toxin type A or other muscle relaxants.
  • Examine the Jaw Area: The masseter muscle must be large enough to treat. Small muscles won’t give good results.
  • Discuss Pain Relief: Some seek Xeomin for jaw pain relief. Confirm that their main goal aligns with the treatment’s offerings.
  • Rule Out Skin Issues: No injections if there’s infection or inflammation in the treatment area.
  • Consider Age Restrictions: Ideal candidates are usually adults who have completed facial growth.
  • Talk About Timing: Xeomin takes time to work. Ensure patients can wait for results before any major event.
  • Review Medication Use: Some medicines can increase bruising or bleeding risks during injections.
  • Prepare for Upkeep: Inform them about the possible need for future sessions to maintain results.
  • Screen Carefully for Contraindications: Certain conditions, like neuromuscular disorders, make Xeomin unsafe.

Common Adverse Effects and Mitigation Strategies

Patients may experience side effects such as swelling, bruising, or discomfort at the injection sites. Rarely, muscle weakness or difficulty chewing may occur. It’s essential to thoroughly discuss these potential risks with patients before treatment. 

Following proper aftercare, including using ice packs and avoiding rubbing the treated area, can help minimize swelling and bruising, ensuring optimal outcomes and patient satisfaction.

Enhancing Patient Satisfaction and Long-Term Results

Follow-up care is crucial for long-term results and patient satisfaction with Xeomin masseter treatments. Regular check-ins allow progress monitoring and adjustments. Setting realistic expectations and offering tips for minimizing discomfort and optimizing healing enhance satisfaction. 

When patients ask questions like, “Which lasts longer between Xeomin or Botox?” Clear communication and prompt reporting are necessary, especially regarding changes, for effective ongoing care. Encouraging adherence to maintenance sessions sustains the desired jawline shape and ensures comprehensive patient wellness.


Xeomin offers a valuable solution for jaw slimming and facial contouring, with its ability to target the masseter muscle and refine the lower facial profile. By understanding the masseter muscle anatomy, calculating the optimal dosage, and employing precise administration techniques, practitioners can deliver safe and effective Xeomin treatments for jawline slimming. 


1. What is Xeomin used for?

Xeomin is a medication approved by the FDA for various purposes, including treating cervical dystonia, smoothing frown lines, and more.

2. How does Xeomin help with jaw slimming?

Xeomin is injected into the masseter muscle, which relaxes it, resulting in a softer and slimmer jawline appearance.

3. Is there a big difference between Xeomin and other treatments like Botox or Dysport?

While Xeomin, Botox, and Dysport are all used to combat wrinkles, each has unique characteristics, such as duration and onset of results.

4. How long before I see my jaw looking slimmer with Xeomin?

Results usually start becoming noticeable within a week after the injection, but the full effect may take up to two weeks.


Shome D, Vadera S, Shiva Ram M, Kapoor R. Efficacy of Incobotulinum toxin‐A for the treatment of masseter muscle hypertrophy in Asian Indian patients: A 2‐year follow‐up study. Journal of Cosmetic Dermatology. 2020;19(8):1892-1899. doi:https://doi.org/10.1111/jocd.13552

Masseter Botox: About, Procedure, Side Effects & More. Healthline. Published January 7, 2021. Accessed May 3, 2024. https://www.healthline.com/health/masseter-botox 



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