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Latisse Vs Grandelash – How To Decide

David Fuller

Last Updated On: June 5, 2024

A survey revealed that three out of four women in the US feel their lash length, thickness, or color needs to be improved. With numerous options available, choosing the right product to make your lashes look longer and healthier can be overwhelming.

Latisse and GrandeLASH are two leading eyelash treatments competing in today’s market. Latisse, a prescription medication, is known for its dramatic results, while GrandeLASH, developed by Alicia Grande, features a blend of amino acids, vitamins, and peptides. Both offer unique benefits for achieving longer, fuller lashes.

In this article, we will compare Latisse and Grandelash, examining their ingredients, effectiveness, and potential side effects to help patients decide which lash treatment is best for them.

Key Takeaways

  • Latisse and GrandeLash contain different active ingredients and work through distinct mechanisms.
  • Both treatments have garnered a loyal following for their ability to enhance eyelash appearance.
  • While Latisse and GrandeLash are generally considered safe when used as directed, they can cause side effects in some individuals.
  • Common side effects of Latisse include eye irritation, itching, and darkening of the eyelid skin, which typically resolve upon discontinuation. 

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Latisse online, contact our sales department for more information.

Understanding Latisse and GrandeLASH

Latisse and GrandeLASH are top choices for lash growth. Latisse requires a doctor’s note, while GrandeLASH is available over the counter. Latisse is known for significant results but requires a prescription, while GrandeLASH shows quick results and is easily accessible. Both have unique benefits and potential side effects, so consider your preferences and needs before choosing.

Active Ingredients and Mechanisms of Action

Knowing what makes Latisse and GrandeLASH work is vital in the battle of Latisse vs. GrandeLASH. Latisse contains bimatoprost as its active ingredient, a prostaglandin analog that lengthens the growth phase of eyelashes, resulting in longer and sometimes thicker lashes over time. However, potential side effects such as orbital fat loss or hypopigmentation should be considered. 

On the other hand, GrandeLASH uses a blend of vitamins, antioxidants, and amino acids, including a prostaglandin analog similar to Latisse, to improve the look of lashes. It also includes moisturizers and plant extracts that nourish and strengthen lashes. GrandeLASH is available over the counter and does not require a prescription, offering an easy-to-use solution.

Both products aim to promote lash growth, but users must understand the potential benefits and risks associated with each option entirely.

Application Methods

Learning how to use Latisse and GrandeLASH correctly can make all the difference. Find out the best way to apply these serums for stunning results.

How to Apply Latisse

To use Latisse, wash and dry your face, remove makeup, and remove contact lenses. Place one drop of Latisse on the applicator and apply along the base of the upper eyelashes. Avoid touching the eye or lower lid to prevent side effects. 

Blot any extra solution and dispose of the applicator after use. Apply Latisse at night for optimal results. Use a new sterile applicator for each eye to ensure safety. Daily application promotes lash growth while minimizing potential risks.

How to Apply GrandeLASH

Start by ensuring your face is clean and makeup-free. Use the provided brush to apply GrandeLASH along your upper lash line once daily, preferably before bedtime. Consistency is key, with noticeable results after three weeks of dedicated use. 

Avoid overdoing it; one stroke per day is enough. This easy application process has made GrandeLASH popular among those seeking non-prescription lash enhancement.

Clinical Efficacy

Studies highlight the efficacy of Latisse and GrandeLASH for eyelash growth, aiding your decision on which to choose. Clinical trials show Latisse’s active ingredient, bimatoprost, significantly enhances lash length and thickness within weeks, with users noticing fuller lashes. Its rigorous testing and clinical backing distinguish it from over-the-counter serums, although rare side effects like orbital fat loss are documented.

Image courtesy of Dermacare Brickell

Conversely, GrandeLASH, an over-the-counter product, also shows promising results. Thanks to its blend of moisturizers and plant extracts, users report darker, fuller lashes in three weeks. 

Image courtesy of The Plastic Surgery Clinic

While both serums contain prostaglandin analogs to promote growth, GrandeLASH does not have the documented concerns of orbital fat loss and other side effects seen with Latisse. Thus, GrandeLASH offers a more accessible option for similar benefits, possibly less potent over time.

Comparison of Clinical Efficacy

Clinical studies comparing Latisse and GrandeLASH show both products effectively promote lash growth. Latisse, a prescription product, significantly boosts lash growth but may plateau over time. GrandeLASH-MD Eyelash serum, an over-the-counter product, yields darker, fuller lashes within three weeks, rivaling Latisse’s results. 

Choosing between them involves considering the need for a prescription, the speed of initial results, and personal preferences. Both products promote lash growth through prostaglandin analogs, making personal preferences a critical factor in decision-making.

Benefits and Potential Side Effects

Latisse and GrandeLASH can make lashes look fuller and longer, but both have side effects. Latisse may cause orbital fat loss, dark spots, or lighter eye colors, while GrandeLASH has milder issues. Latisse’s active ingredient leads to significant lash growth and is available as a prescription. 

GrandeLASH, an over-the-counter option, promotes lash growth with moisturizers and plant extracts. Both serums have revolutionized lash care, providing alternatives to extensions and heavy makeup.

Latisse lash serum before and after photos show impressive transformations, while GrandeLASH is celebrated for quick improvements in darkness and fullness of lashes. The choice between them depends on individual needs and preferences.

Potential Side Effects of Latisse and GrandeLASH

Both Latisse and GrandeLASH can cause side effects. Some people might see their eye color change, which can last long. Also, the skin around the eyes could get darker. If you use it more than necessary, your eyelids might swell or itch, and your eyes feel dry.

GrandeLASH also has side effects, but they are different. Your eyes might get red or feel irritated. Sometimes, the area where you apply GrandeLASH gets itchy or red too. Most of these problems go away after a short time of using it.

Ideal Patient Profiles

Finding a suitable lash serum can be challenging. Latisse is ideal for those seeking significant lash growth improvement and willing to commit to prescription treatment. Potential side effects include long-term iris color change, especially for those with lighter eye colors. 

GrandeLASH offers an over-the-counter option with less potent effects, appealing to individuals desiring quick improvements with fewer risks. Choosing between Latisse and GrandeLASH depends on personal eyelash goals and health considerations.

Expert Opinions and Recommendations

Dermatologists and ophthalmologists often prescribe Latisse for patients seeking longer, thicker lashes. It contains bimatoprost, a prostaglandin analog that extends the growth phase of lash follicles.

Many patients report noticeable improvements in lash length, darkness, and fullness after consistent use. However, it requires a prescription and may cause side effects like eye redness or darkening of the iris.

GrandeLASH, a non-prescription serum, is popular among beauty professionals. It contains amino acids, vitamins, and peptides to nourish lashes and promote growth. While less potent than Latisse, GrandeLASH can enhance lash appearance over time. Some experts recommend it for those seeking a more natural option without potential side effects.

In summary, both treatments have their merits. Latisse offers robust results but requires a prescription, while GrandeLASH provides a gentler alternative. Always consult a professional before starting any lash treatment.


Choosing between Latisse and GrandeLash depends on your needs. If you want strong lash growth and don’t mind seeing a doctor, Latisse could be for you. But if you prefer something over the counter, try GrandeLash. Both have their perks and side effects. So, think about what works best for your lashes and lifestyle. Your perfect eyelash serum is out there!


1. What’s the main difference between Latisse and Grandelash?

The main difference between Latisse and Grandelash lies in their active ingredients. Latisse uses a component known to make lashes grow longer over time, while Grandelash aims to enhance lash volume with its unique blend.

2. Can I see results quickly with either product?

Results with both products may vary. Latisse users often notice noticeable changes with the regular application per the recommended dosage. Grandelash may also show results, but it requires some time.

3. Are there any side effects I should worry about?

It’s essential to be aware of potential side effects. Latisse may lead to long-term side effects such as hypopigmentation or changes if used during pregnancy. Consulting a doctor before use is recommended.

4. Is one safer than the other for long-term use?

Both products have their pros and cons. Managing potential issues with Latisse involves monitoring dosage. Safety concerns should be addressed through personal research and professional advice.


Inc A. Survey Shows 3 out of 4 Women in the U.S. (ages 18-65) Think the Length, Thickness, or Color of Their Eyelashes is Inadequate(1). www.prnewswire.com. https://www.prnewswire.com/news-releases/survey-shows-3-out-of-4-women-in-the-us-ages-18-65-think-the-length-thickness-or-color-of-their-eyelashes-is-inadequate1-250055331.html

Bitton E, Courey C, Giancola P, Diaconu V, Wise J, Wittich W. Effects of LATISSE (bimatoprost 0.03 per cent topical solution) on the ocular surface. Clinical and Experimental Optometry. 2017;100(6):583-589. doi:10.1111/cxo.12507



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