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Revanesse vs Restylane: A Comparison of Dermal Fillers

David Fuller

Last Updated On: June 20, 2024

Did you know that minimally invasive dermal fillers are increasingly popular among individuals seeking facial rejuvenation? Recent studies and reports have revealed that more and more people are opting for these non-surgical treatments to enhance their appearance. 

Among the top dermal fillers, Revanesse is a standout. Created by Prollenium Medical Technologies, Inc., Revanesse uses advanced technology and a unique formula. This combination makes the hyaluronic acid molecules smooth and round, allowing for smoother volume enhancement that degrades gradually. 

In this article, we’ll compare Revanesse and Restylane, analyze their formulation longevity, and help you make an informed choice for your aesthetic goals.

Key Takeaways

  • Revanesse and Restylane are fillers that use hyaluronic acid to help make skin look smoother and fuller. They work well for lips and wrinkles.
  • The feel of the gel, how long the results last, and patient comfort differ between Revanesse and Restylane. These things can affect which filler a doctor might choose.
  • Doctors like using both fillers. Studies show they’re safe, make patients happy with their looks, and have long-lasting effects.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. Buy Revanesse online at Med Supply Solutions today and stock your practice at wholesale prices!

Introduction to Revanesse and Restylane

Revanesse Ultra and Restylane are top choices for reducing wrinkles and adding facial volume. Both use hyaluronic acid but have fundamental differences. Restylane employs non-animal stabilized hyaluronic acid (NASHA), making it highly effective and popular. Revanesse, although newer, offers high-quality results in lip fullness and facial rejuvenation. 

Experts note that finding Revanesse can be more challenging than Restylane. Both target deep skin lines with mid-to-deep injections, but one might suit individual needs better. Among various filler options like Radiesse, choosing between Revanesse and Restylane is an adventure in beauty care.

Gel Firmness and Composition

Understanding the characteristics of dermal fillers is crucial for medical professionals to make informed decisions for their patients. This includes examining the gel firmness of Revanesse and Restylane, which impacts both the injection process and the aesthetic outcomes. The following table outlines a comparison between these two popular fillers based on their gel firmness:

Gel FirmnessRevanesse tends to have a slightly softer consistency.Restylane offers a range of firmness levels across its product line, catering to different treatment areas.
Injection TechniqueThe softer consistency of Revanesse may allow for smoother injections in delicate areas.Restylane’s variable firmness requires adept technique adjustments by the injector for optimal placement.
Target AreasBest suited for fine lines and areas requiring subtle volume.Its range makes it effective for fine lines and deeper folds by selecting the appropriate product variant.
Patient ComfortPatients report minimal discomfort due to the gel’s softer nature.The experience may vary depending on the specific Restylane product and treatment area.
Aesthetic OutcomeProvides a natural look, especially in areas requiring precision like the lips.Capable of achieving both subtle enhancements and more significant volume increases, depending on the chosen product.

Analysis of the Composition of Each Dermal Filler

Revanesse and Restylane use hyaluronic acid to add volume and smooth wrinkles but differ in formulation. Revanesse’s smooth gel ensures even distribution for a natural look, while Restylane’s NASHA technology creates firmer gels for deeper folds and more volume. 

Restylane Kysse targets lips for long-lasting fullness, whereas Revanesse Versa causes less swelling, ensuring a quicker recovery. Both fillers aim for patient satisfaction with unique mixtures and technologies tailored to different needs, making them top choices for facial rejuvenation.

Ease of Injection and Patient Comfort

Finding a suitable dermal filler can be tricky, but knowing how easy a filler is to inject and how it makes patients feel during and after the process helps. Doctors find Revanesse and Restylane easy to work with, noting that these fillers flow smoothly into the skin. 

This makes the treatment less stressful for patients and doctors alike. Revanesse might feel a bit smoother during injection than Restylane. People worry less about pain with both options. The smooth injection ensures comfort, and patients often say it wasn’t as bad as they thought. 

The Injection Room recommends Restylane Kysse or Revanesse Versa for lips. After treatment, minor discomfort, swelling, or redness is common but resolves quickly. Revanesse and Restylane offer a smooth recovery period, allowing most people to resume normal activities soon after their visit. Whether choosing Revanesse Versa or Restylane, patient comfort remains a top priority for achieving smoother skin or fuller lips.

Aesthetic Outcomes and Longevity

Comparing the aesthetic outcomes of Revanesse and Restylane reveals valuable insights for medical professionals aiming to deliver optimal patient results. Let’s explore how these two dermal fillers enhance facial aesthetics.

Lip FullnessDelivers subtle and natural-looking enhancementKnown for creating pronounced yet smooth results
Wrinkle ReductionEffectively smooths out moderate to severe lines with precisionHighly effective in addressing deep wrinkles, offering lasting smoothness
Longevity of ResultsResults can last up to 12 months, with variations depending on individual factorsTypically lasts between 6 to 18 months, influenced by treatment area and patient’s skin
Product AccessibilityLess accessible compared to Restylane, potentially affecting the patient preferenceWidely available, making it a go-to option for many practitioners
Tolerability and Patient ComfortWell-tolerated with minimal discomfort during and after injectionSimilar in tolerability, with an emphasis on patient comfort during the procedure

Image courtesy of The Glasgow Skin Clinic

This patient sought help for volume loss in her cheeks and dark circles under her eyes. Restylane injections gave her subtle yet effective results, restoring volume and reducing dark circles.

Image courtesy of McKenzie Health System

The patient underwent a Revanesse® Versa treatment. This natural hyaluronic acid dermal filler, clinically tested and FDA-approved, effectively helped achieve the patient’s beauty goals.

Assessment of the Longevity of Results for Each Dermal Filler

Revanesse and Restylane fillers offer long-lasting enhancements depending on the area treated and individual skin characteristics. While Revanesse results may persist for up to 12 months, Restylane often provides visible effects for about 6 to 18 months. Experts recommend proper aftercare and regular touch-up sessions to maintain desired outcomes. Additionally, lifestyle factors and hydration extend the benefits of dermal fillers.

Expert Opinions and Clinical Studies

Revanesse and Restylane are top choices for achieving fuller lips and smoother skin. Recent studies have shown that both fillers effectively smooth out wrinkles, providing long-lasting results. Doctors and researchers confirm the safety and efficacy of these fillers, ensuring patients are satisfied with their outcomes. 

The choice between Revanesse and Restylane often depends on individual preferences and needs. Both options offer a comfortable way to achieve fuller lips and reduce facial lines, making them popular choices among patients looking to enhance their appearance.


Choosing between Revanesse and Restylane depends on your needs. Each filler has its perks, from how long it lasts to how it feels. Doctors think both are great for making lips fuller and smoothing wrinkles. It boils down to your skin type and what look you want. Talk with a pro to find out which is best for you.


1. What are the primary differences between Revanesse and Restylane?

Revanesse and Restylane are both types of dermal fillers, but they have different compositions. Revanesse generally provides a smoother feel, while Restylane offers a variety of formulations tailored for specific areas.

2. Can I expect immediate results after using Revanesse or Restylane?

Absolutely! You’ll notice visible changes shortly after receiving either Revanesse or Restylane fillers. However, individual experiences may vary.

3. Is one filler better suited for first-time users?

The choice between Revanesse and Restylane depends on your specific needs and preferences. Some individuals prefer Revanesse for its smooth finish, while others opt for Restylane due to its effectiveness in targeting specific facial areas.

4. How long do the effects of Revanesse and Restylane last?

Both Revanesse and Restylane fillers typically last between 6 to 18 months. However, the duration may vary based on the specific product used, such as Revanesse Ultra, and individual factors like your body’s response to the filler.


Fabi S, Alexiades M, Chatrath V, et al. Facial Aesthetic Priorities and Concerns: A Physician and Patient Perception Global Survey. Aesthetic Surgery Journal. 2021;42(4):NP218-NP229. doi:https://doi.org/10.1093/asj/sjab358 

Radiesse vs. Restylane: Comparing the Two Dermal Fillers. Healthline. https://www.healthline.com/health/radiesse-vs-restylane



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