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Lumigan Generic Name – All About Bimatoprost

David Fuller

Last Updated On: June 15, 2024

Recent studies have shown that bimatoprost, a synthetic prostamide, is highly effective in treating ocular conditions such as glaucoma and ocular hypertension. Its ability to reduce intraocular pressure (IOP) by increasing the outflow of aqueous humor is a significant breakthrough in ophthalmic medicine.

For those unfamiliar with bimatoprost, it is widely recognized by its commercial name, Lumigan. This medication has revolutionized treatment options and offered hope for patients seeking alternatives to surgery.

In this article, we will delve into the world of Lumigan, exploring its properties, mechanism of action, and its impact on eye care.

Key Takeaways

  • Bimatoprost, the generic name for Lumigan, treats glaucoma, ocular hypertension, and eyelash hypotrichosis.
  • It works as a prostaglandin analog, enhancing eyelash growth by prolonging the anagen phase of the hair growth cycle.
  • Besides lowering intraocular pressure, Bimatoprost is used cosmetically to promote eyelash growth.
  • Understanding Bimatoprost’s development and regulatory history helps medical professionals utilize it effectively in treatment plans.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Lumigan online, contact our sales department for more information.

Pharmacological Properties of Bimatoprost

Bimatoprost, Lumigan’s active ingredient, is a synthetic compound designed to mimic natural fatty acids that maintain healthy eye pressure. It targets specific receptors in the eye, making it practical for treating glaucoma and ocular hypertension by enhancing fluid outflow. 

With a molecular formula of C25H37NO4, Bimatoprost binds to prostaglandin receptors, reducing intraocular pressure and promoting eyelash growth. Bimatoprost is quickly absorbed upon application, reaching peak blood levels in about 10 minutes and nearly disappearing after 1.5 hours. It works by imitating prostaglandins, increasing fluid drainage from the eye to lower pressure. 

This action helps prevent optic nerve damage and vision loss in glaucoma patients. Bimatoprost’s dual action on eye pressure and eyelash growth highlights its versatile benefits, making it a critical treatment for ocular conditions and a popular off-label choice for enhancing eyelashes.

Mechanism of Action of Bimatoprost

Bimatoprost is crucial for managing high eye pressure and promoting eyelash growth. It increases fluid outflow, effectively treating glaucoma and ocular hypertension by targeting specific receptors to boost aqueous humor drainage. 

Its precise action reduces intraocular pressure without altering other eye functions. This mechanism also explains its off-label use for eyelash growth, making Lumigan a versatile treatment. By imitating the body’s processes, bimatoprost offers a safe, efficient solution for managing high eye pressure and promoting eyelash growth. 

Clinical Applications of Bimatoprost

  • Treatment of Glaucoma: Doctors prescribe Lumigan (bimatoprost) to treat glaucoma by reducing eye pressure through increased fluid outflow. Patients apply these drops daily. Potential side effects include eye color changes and longer, thicker eyelashes, which should be discussed before starting treatment. Effective glaucoma management requires regular monitoring and treatment adjustments.
  • Management of Ocular Hypertension: Bimatoprost (Lumigan) treats ocular hypertension and glaucoma by improving fluid drainage to lower eye pressure. Patients use these drops daily to prevent vision loss. Side effects may include longer eyelashes or eye color changes, so regular monitoring is essential for safe, effective treatment.
  • Off-label Uses in Ophthalmology: Doctors use Lumigan (bimatoprost) for glaucoma to lower eye pressure and off-label to promote eyelash growth and darken eye color. It’s recommended for thin lashes (hypotrichosis) due to its side effect of fuller lashes. Regular monitoring ensures safe and effective treatment.

Development and Regulatory Approval of Bimatoprost

Research and clinical trials play a vital role in medicine. They help us understand how treatments like Lumigan (bimatoprost) work for different conditions, including glaucoma and eyelash hypotrichosis.

Image courtesy of Trikwan

Lumigan, known for its glaucoma treatment, has gained attention for eyelash enhancement. Studies, including one from the University of California, have explored its off-label use, revealing promising results for eyelash growth in alopecia areata patients. Research indicates that Lumigan can safely increase eyelash prominence when applied topically.

Image courtesy of okdermo

Clinical trials further support Lumigan’s efficacy. A multicenter study comparing bimatoprost 0.03% with a placebo found significant improvements in eyelash length, thickness, and darkness. Participants using Lumigan experienced noticeable enhancements, affirming its potential beyond glaucoma care.

Long-term studies, such as a year-long trial with 560 patients, have demonstrated Lumigan’s consistent performance. It maintained intraocular pressure reduction over 12 months, showcasing a reliable safety profile. These findings suggest Lumigan’s dual benefits for ocular pressure management and cosmetic eyelash treatment.

FDA Approval Process

The FDA approval process for Bimatoprost involved a thorough review of the preclinical and clinical trial data submitted by the manufacturer. The New Drug Application (NDA) included comprehensive information on the drug’s pharmacology, toxicology, and clinical efficacy and safety. The FDA’s Center for Drug Evaluation and Research (CDER) reviewed this data to ensure that Bimatoprost met the stringent safety, efficacy, and quality standards.

In 2001, the FDA approved Bimatoprost under the name Lumigan for treating glaucoma and ocular hypertension. This approval was based on the positive outcomes from clinical trials, which demonstrated significant reductions in intraocular pressure compared to placebo and other standard treatments. It also involved post-marketing surveillance to monitor the long-term safety and effectiveness of the drug in the general population.

Safety and Efficacy Assessments

After bimatoprost’s FDA approval, experts tested its safety and efficacy through ongoing studies and post-marketing surveillance. These assessments confirmed the long-term effectiveness of Bimatoprost in reducing intraocular pressure. Common side effects included eye redness, eyelash growth, and ocular pruritus, which were generally mild to moderate. Rare but serious adverse effects, such as macular edema and bacterial keratitis, were also monitored to ensure patient safety.

Other Uses of Bimatoprost

Bimatoprost, or Lumigan, helps treat eyelash hypotrichosis by promoting longer, thicker, and darker lashes. Initially used for eye conditions, it has unexpectedly become a cosmetic dermatology interest. Patients using Lumigan noticed improved skin and accidental drops suggested skin benefits. 

Dermatologists are exploring its potential to improve skin appearance, reduce wrinkles, and make the skin look younger without surgery. Additionally, researchers are investigating bimatoprost’s potential to treat other eye conditions beyond changing eye color and promoting eyelash growth.


Bimatoprost, known as Lumigan, plays a significant role in eye care. It treats glaucoma, helps lower eye pressure, and promotes eyelash growth. Research about bimatoprost, such as those comparing Lumigan vs Latanoprost, continues to show more ways to use the treatment, making it a crucial player in maintaining eye health.


1. What is the generic name for Lumigan?

The generic name for Lumigan is Bimatoprost. Doctors use it to help with certain eye conditions.

2. Can using Lumigan change the color of my eyes?

Yes, it’s possible! When you use Lumigan, you might notice your eye color changing. This happens because of how Bimatoprost works in your body.

3. Is Bimatoprost only for treating eye problems?

While its main job is to treat eye issues, doctors sometimes find other uses for it, too. But yes, its significant role is in helping with eye conditions.

4. How does Lumigan work in the body?

As its scientific name suggests, Lumigan, or Bimatoprost, works by increasing fluid flow out of the eye. This helps lower pressure inside the eyes and keeps them healthy.


Kammer JA, Katzman B, Ackerman SL, Hollander DA. Efficacy and tolerability of bimatoprost versus travoprost in patients previously on latanoprost: a 3-month, randomised, masked-evaluator, multicentre study. British journal of ophthalmology. 2009;94(1):74-79. doi:https://doi.org/10.1136/bjo.2009.158071

Wadhwa A, Jadhav C, Yadav KS. Bimatoprost: Promising novel drug delivery systems in treatment of glaucoma. Journal of Drug Delivery Science and Technology. 2022;69:103156. doi:https://doi.org/10.1016/j.jddst.2022.103156 



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