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Lumingan Change Eye Color – Why It Happens

David Fuller

Last Updated On: June 18, 2024

Eye drops and eye wash are not just products but staples in the lives of many Americans, with an impressive 117.45 million people using them in 2020. This widespread reliance on ocular solutions underscores the shared experience and importance of understanding these products’ benefits and potential side effects.

Lumigan, known generically as bimatoprost, is often prescribed for glaucoma but has side effects. Patients may experience eye redness, irritation, changes in eyelash growth, and, in rare cases, more severe reactions, such as a change in eye color. Understanding these side effects is essential for informed usage.

In this article, we’ll explore the science and implications of Lumigan-induced eye color change, uncovering the reasons behind this phenomenon.

Key Takeaways

  • Lumigan, a medication containing the active ingredient Bimatoprost, has been associated with the side effect of changing eye color.
  • Bimatoprost’s mechanism of action involves increasing the pigmentation of the iris, leading to a change in eye color.
  • Clinical studies have provided evidence supporting the link between Lumigan use and eye color change.
  • The prevalence of eye color change in patients using Lumigan and the permanence of this change after discontinuation of the medication vary among individuals.
  • Due to unexpected eye color changes, patients using Lumigan may experience psychological and social implications, and healthcare professionals need to provide counseling and manage their expectations effectively.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Lumigan online, contact our sales department for more information.

The Science Behind Lumigan and Eye Color Change

Lumigan eye drops for glaucoma, a medication for eye problems, can cause changes in eye color due to its active ingredient, bimatoprost. While it reduces intraocular pressure, one potential side effect of bimatoprost is changes in eye color. This occurs because bimatoprost impacts pigment cells in the iris, potentially resulting in a darkened eye color over time. 

This side effect is more common in people with mixed-color eyes, such as blue, gray, yellow, or green. Once the eye color changes, it is usually permanent. Bimatoprost increases melanin levels in the iris, the pigment responsible for eye color, leading to this darkening effect with regular use.

The darkening effect is more noticeable in individuals with lighter eye colors and can persist even after discontinuing the medication. Understanding how bimatoprost influences melanin production helps medical professionals manage patient expectations and provides insight into Lumigan’s potential side effects.

Clinical Studies on Lumigan and Eye Color Change

Key findings in various clinical studies confirm the connection between changes in eye color, such as the following:

  • One of Lumigan’s known side effects is a change in eye color, particularly an increase in brown pigmentation. This effect is more commonly observed among women and people over 60, especially after taking the drug for 6 to 12 months.
  • The change in eye color is attributed to the increased pigmentation of the iris, which may be permanent. Lumigan can also cause darkening of the eyelid skin and eyelashes, which may be reversible after treatment is stopped. It’s important to note that the long-term effects of the increased dark coloring are not fully known.
  • Postaglandin-associated periorbitopathy (PAP) is a condition that involves changes such as increased pigmentation of the iris and skin around the eyes, which is linked to prostaglandin analogs like bimatoprost.

Each piece of research contributes to understanding why and how Lumigan can alter eye color, emphasizing the need for awareness among medical professionals prescribing this medication for either glaucoma or eyelash enhancement.

Prevalence and Permanence of Eye Color Changes

Many people using Lumigan may experience a change in eye color, which can persist even after discontinuing the medication. This side effect is uncommon, with studies showing that only a small percentage of users are affected.

People with blue, green, or hazel eyes might notice their eye color turning more brownish after several months of consistent use. This change is permanent and does not reverse even years after stopping Lumigan. Patients considering this treatment should be aware of this potential long-term effect on their appearance.

Factors Influencing the Permanence of Eye Color Change

Several factors influence the permanence of eye color changes experienced by patients using Lumigan (bimatoprost). Understanding these factors can help patients and healthcare providers manage expectations and make informed decisions about treatment.

  • Duration of Use: The length of time a patient uses Lumigan significantly impacts the likelihood and permanence of eye color changes. Longer-term use is more likely to result in noticeable and permanent pigmentation changes. Patients who use Lumigan for several months or years are at a higher risk of experiencing these irreversible effects.
  • Original Eye Color: As previously discussed, individuals with lighter eye colors, such as blue, green, or hazel, are more susceptible to changes in pigmentation. The active ingredient in Lumigan, bimatoprost, increases melanin production in the iris, causing a gradual darkening effect. Those with mixed-color eyes may notice a more pronounced change compared to those with darker eyes.
  • Consistency of Application: Regular, daily use can lead to a cumulative effect, increasing the likelihood of permanent pigmentation changes. Patients who apply the medication sporadically may be less likely to experience significant changes.
  • Genetics: Each patient’s biological response to bimatoprost can vary. Some individuals may be more prone to melanin production and subsequent eye color changes. Genetic factors and individual differences in iris pigmentation can influence how noticeable and permanent the changes will be.
  • Cumulative Dosage: The overall amount of bimatoprost a patient is exposed to over time can impact the extent of eye color changes. Higher cumulative dosages, resulting from consistent and prolonged use, are more likely to cause permanent alterations in iris pigmentation.

Potential Implications for Patients

Lumigan can change eye color, often making it more brown, which surprises and worries many users. This side effect, common with Lumigan and Latisse, can cause mixed reactions and have a psychological impact. Some find it exciting, while others feel stressed or sad. Doctors must discuss this possibility to help patients manage expectations and cope with any changes.

There are also social and cultural considerations because Lumigan may alter a patient’s eye color.In some cultures, eye color holds deep meanings or beauty standards, so Lumigan’s ability to change it can impact self-identity and perception.

Doctors must discuss potential changes carefully, considering patients’ backgrounds and the broader impact on their lives. Understanding this can help manage expectations and address concerns about appearance shifts caused by the medication.

Managing Patient Concerns

When patients worry about their eye color changing due to Lumigan, doctors listen and help. They offer clear facts and other choices if they feel they need clarification. Lumigan can sometimes shift a patient’s eye color, which worries some patients.

  • Listen carefully to the patient’s concerns about Lumigan changing their eye color.
  • Explain the science behind how Lumigan or Bimatoprost affects iris pigmentation.
  • Share statistics on how often this eye color change happens with Lumigan users.
  • Discuss the permanence of the eye color change, clarifying that it can be lasting.
  • Compare Lumigan and Latisse, highlighting their uses and potential for causing eye color changes.
  • Offer stories or case studies of other patients who have experienced similar changes.
  • Assure patients that their health is the priority, and cosmetic changes are secondary but taken seriously.
  • Talk about alternatives to Lumigan for those concerned about changing their eye color.
  • Reassure them with professional guidance customized to treat their condition and manage expectations regarding eye color shifts.


Lumigan can darken eye color by increasing iris pigment. Although not universal, the change is often permanent. Some find joy in this surprise, embracing their new eye color. Educating patients about Lumigan’s effects fosters understanding and appreciation for potential outcomes, aiding in managing expectations and finding delight in unexpected transformations.


1. What is Lumigan, and how does it change eye color?

Lumigan treats eye conditions but may darken eye color as a side effect.

2. Is Lumigan the same as Latisse?

Lumigan improves eye health, while Latisse lengthens eyelashes.

3. Why does Lumigan change eye color?

Lumigan increases iris melanin, darkening eye color.

4. Will Lumigan change my eye color?

Eye color change varies; some notice darkening, while others see no difference.


U.S.: usage of eye drops and eye wash 2020. Statista. https://www.statista.com/statistics/275642/us-households-usage-of-eye-drops-and-eye-wash/

MSN. www.msn.com. https://www.msn.com/en-us/health/drugs/in-lumigan/in-lumigan 



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