Business Hours: Monday-Friday 9AM-6PM EST

Featured Image

Ellanse vs. Sculptra – Comparing Dermal Fillers

David Fuller

Last Updated On: June 23, 2024

Over the years, the aesthetic industry saw a rise in dermal filler use from 1.7 million in 2010 to 3.4 million procedures performed in 2020. These numbers reflect a growing preference for non-surgical cosmetic enhancements, showing the demand for treatments that deliver lasting results without invasive procedures.

Among the leading dermal fillers are Ellanse and Sculptra. Both are designed to combat facial aging by addressing wrinkles and restoring volume with unique formulations. Choosing between them hinges on factors like treatment goals, the longevity of effects, and individual skin needs, showcasing the versatility and effectiveness of modern injectables.

This article compares Ellanse and Sculptra, exploring their distinct properties, duration, and patient satisfaction.

Key Takeaways

  • Ellanse and Sculptra help make skin look younger by boosting collagen, but they work differently. Ellanse gives immediate results lasting up to 4 years, while Sculptra improves skin over time with effects lasting about 2 years.
  • Safety is vital for both fillers. Even though Ellanse doesn’t have FDA approval like Ellanse, both fillers have good safety records with minor side effects like swelling or redness at the injection site.
  • The cost of treatment varies. Sculptra might need more sessions, which could increase the price, while Ellanse’s long-lasting effects may offer better value over time despite a higher initial cost per session.

About: Operating since 2016, Med Supply Solutions is known for being one of the industry’s top and trusted suppliers of cosmetic and viscosupplementation products. If you’re looking to buy Ellanse online, contact our sales department for more information.

Introduction to Ellanse and Sculptra

Dermal fillers are non-invasive treatments that inject substances beneath the skin to restore volume, smooth wrinkles, and plump lips. This stimulates collagen production, a protein that keeps skin firm and youthful. As we age, collagen declines, leading to wrinkles and sagging. Fillers like Ellanse and Sculptra address this by boosting collagen and enhancing facial features.

Ellanse provides immediate results lasting up to four years, which is ideal for those seeking quick and long-lasting improvement. Sculptra, on the other hand, works gradually over months to achieve smoother texture and volume that lasts around two years. While only Sculptra is FDA-approved, both Sculptra and Ellanse are considered generally safe, with minor side effects possible. 

When choosing, consider your desired speed of results, longevity of impact, and budget. Ellanse offers a combination of immediate wrinkle filling and collagen stimulation, while Sculptra provides a gradual, biocompatible approach to volume restoration.

Composition and Mechanism of Action

Ellanse fillers and Sculptra improve skin quality by stimulating natural collagen production. Ellanse, with its biodegradable PCL material, nurtures new skin support structures to flourish naturally, while Sculptra collaborates with the body using PLLA to restore lost collagen. 

Both initiate post-injection collagen production, gradually enhancing skin appearance over months without leaving residual foreign substances in the body. Patients typically notice improved facial volume and contouring after approximately three treatment sessions over several months.

Efficacy and Safety Profiles

Clinical trial data and expert reviews must be examined closer to illuminate Ellanse’s efficacy. Ellanse, known for its unique action of stimulating collagen production, is a formidable player among dermal fillers.

Image courtesy of River Aesthetics

Ellanse’s before-and-after results prove this filler’s worth in the aesthetic field because it delivers high satisfaction with minimal side effects. Clinical reviews suggest its effectiveness in facial rejuvenation, especially in the nasolabial fold area, with lasting improvements and typical minor complications.

Patient testimonials and an 89% “Worth It” rating on RealSelf reflect Ellansé’s success in restoring facial volume and reducing lines. While not FDA-approved in the U.S., its performance in other regions indicates a strong potential for broader acceptance.

Meanwhile, Sculptra is a notable dermal filler in cosmetic dermatology. It primarily comprises poly-L-lactic acid (PLLA), which stimulates collagen production, enhancing gradual and lasting facial volume.

Image courtesy of Primera Plastic Surgery Med Spa

Clinical studies validate Sculptra’s efficacy. A double-blinded trial showed improved cellulite appearance and skin firmness lasting up to a year. Another confirmed Sculptra’s long-term effect on cheek wrinkles, which has maintained improvement over two years.

Patient reviews on RealSelf and dermatologists endorse Sculptra’s natural volumizing through collagen stimulation, which is suitable for various ages, reflecting its broad appeal and effectiveness.

Safety Profiles of Ellanse and Sculptra

Sculptra is the only filler between the two that has received FDA approval in the United States. However, Ellanse’s ingredients are FDA-approved for use in medical devices like dermal fillers.

  • Ellanse stimulates collagen with minimal side effects, like temporary redness or swelling, offering significant improvements and lasting impact. Due to its biocompatible nature, doctors highlight high patient satisfaction and reduced long-term complications.
  • On the other hand, Sculptra effectively rebuilds collagen over time, lasting up to two years with natural-looking results. It’s favored for its gradual skin texture and facial volume improvement and requires less frequent maintenance.

Both filters are reliable, balancing safety, efficacy, and long-term benefits in skin rejuvenation treatments.

Practical Considerations

Ellanse and Sculptra are popular choices for facial rejuvenation, recognized for their ability to stimulate collagen production. Both fillers target different areas for a youthful appearance. Here is a detailed list of treatment areas suitable for each product:

  • Cheeks: Sculptra volumizes hollow cheeks, while Ellanse lifts and enhances cheek definition.
  • Nasolabial Folds: Sculptra reduces these lines over time; Ellanse provides immediate correction and long-term improvement.
  • Marionette Lines: Sculptra softens lines extending from mouth corners to chin; Ellanse effectively fills these lines.
  • Pre-jowl Sulcus: Ellanse addresses sagging around the jawline by stimulating collagen production.
  • Chin Wrinkles: Sculptra gradually fills chin wrinkles, reducing dimpling and creases.
  • Temples: Ellanse and Sculptra restore lost volume in hollow temples, with Sculptra results appearing more gradually.
  • Shallow Contours: Ellanse enhances facial contours immediately and long-term through collagen stimulation.

Patient Preferences for Ellanse and Sculptra

Choosing between Ellanse and Sculptra involves personal preferences and specific needs. Each has unique features that attract different patients.

  • Results Duration: Some patients prefer Ellanse for its long-lasting effects. It can stimulate collagen for up to 4 years.
  • Immediate vs. Gradual Results: Sculptra attracts patients wanting gradual improvements. Its results appear over a few months.
  • Composition and Safety: Patients often research the composition of dermal fillers. Those wary of synthetic materials might lean towards Sculptra, which is made from poly-L-lactic acid.
  • FDA Approval: The FDA’s approval is crucial for many. Patients feel more confident choosing Sculptra because it has passed rigorous safety standards. However, regulatory bodies in other countries where Ellanse is widely used have verified this filler’s safety.
  • Cost Considerations: Budget plays a significant role in decision-making. Sculptra may require multiple sessions initially, affecting overall cost, whereas Ellanse’s longer duration might offer better value over time.
  • Treatment Areas: Individuals have specific areas they want to improve. Sculptra is widely used for larger areas like cheeks and temples, attracting patients with broader rejuvenation goals.
  • Recovery Time: Minimal downtime is a major plus for busy individuals. Both fillers promise quick recovery, but personal experiences vary, influencing preference based on hearsay or personal research.
  • Aesthetic Goals: Those aiming for subtle enhancements may gravitate towards Sculptra, while Ellanse might be the choice for more defined contouring or immediate correction needs.


Ellanse and Sculptra offer distinct approaches to facial rejuvenation through collagen stimulation. Ellanse provides faster, relatively long-lasting results, while Sculptra requires more time but offers prolonged freshness. Choosing between them depends on the desired timing and patience for visible changes. Both are safe, effective choices for reversing signs of aging, ensuring quality results tailored to individual preferences.


1. What is Ellanse, and has it received FDA approval? 

Ellanse is a long-lasting dermal filler renowned for its rejuvenating effects on skin. Yes, Ellanse has been FDA-approved, ensuring adherence to stringent safety standards.

2. How does Sculptra differ from Ellanse in terms of their effects? 

Both Sculptra and Ellanse effectively reduce wrinkles and restore facial volume. However, their approach to stimulating collagen production differs. Sculptra gradually rebuilds natural collagen, while Ellanse typically yields faster results.

3. Are there any restrictions on who can use these fillers? 

Most adults seeking facial rejuvenation can consider them, but consultation with a healthcare professional is crucial to determining the best option for individual needs.

4. Is one filler more suitable for specific facial areas? 

Rather than superiority, the choice between Sculptra and Ellanse depends on specific facial needs. Sculptra may be recommended for deeper wrinkles or more significant volumizing needs, whereas Ellanse might be preferred for targeted precision or quicker results.


Van Wicklin SA. Recommendations for Treatment of Soft-Tissue Filler Complications. Plastic and Aesthetic Nursing. 2022;42(1):7-12. doi:https://doi.org/10.1097/psn.0000000000000424 

Galderma receives FDA approval for Sculptra® for cheek wrinkles. Galderma. https://www.galderma.com/news/galderma-receives-fda-approval-sculptrar-cheek-wrinkles-0 



Log In


Subscribe for exclusive offers and updates on new arrivals




Share feedback at:

[email protected]

Working Hours

Monday to Friday: 9 AM to 6 PM (EST)

The Most Popular Brands

Copyright 2024. Med Supply Solutions