Even in the hands of skilled practitioners, occasional missteps or unexpected outcomes can occur. Thankfully, the realm of aesthetic medicine has the solution.
Mistakes can happen, but with Liporase, they can also be reversed. Today, we’ll explain how to use Liporase, what it is, and what it brings to the table in the ever-advancing field of aesthetic medicine.
Liporase is the brand name for a hyaluronidase enzyme produced by Daehan New Pharm, a South Korean company. Its main use is for dissolving hyaluronic acid fillers, but it can also boost the effects of fat-dissolving injections.
When dissolving HA fillers, Liporase targets only synthetic hyaluronic acid, leaving our own supplies intact. It works by cleaving glycosidic bonds within acids and efficiently turning them into monosaccharides. Once the bonds are broken, the patient’s body will absorb the filler and dispose of it. The whole process is relatively quick, and you can expect to see the filler breaking down around 24 to 48 hours after Liporase usage, but the exact time required will depend on the filler’s location and the brand.
When it comes to the fat dissolving, Liporase prepares the area by weakening the membrane of the surrounding tissue, which speeds up the absorption of the following drug. Before being used primarily as a substitute for breaking down dermal fillers, the hyaluronidase enzyme was used to increase the absorption of anesthesia and other drugs due to its ability to increase absorption in the area.
When you order Liporase from Med Supply Solutions, you will receive 10 vials of powder, which need preparation before use. The recommended dose is to use 1 vial of Liporase with 3cc of saline to dissolve 3cc of hyaluronic acid filler.
To prepare the vial, begin by opening it and adding 1 mL of 0.9% NaCl saline solution. Mix it slowly, don’t shake it, until the powder dissolves, and then add 2 mLs of the same saline and mix them. Once the solution is properly mixed, you can apply it to the desired area.
To effectively dissolve dermal filler with Liporase, you want the now-prepared formula to interact with binding sites within the hyaluronic acid. The fastest way to do this is by injecting the Liporase directly into the dermal filler, but if the filler is within a blood vessel, it’s more than enough to inject it in its close proximity.
Once the Liporase has done its work, the patient has to wait at least 10 days before injecting dermal fillers in the same area.
If you plan to use it to boost fat-dissolving injections like Kybella, the steps are similar, but once you mix the powder with 1 mL of saline solution, instead of 2 mLs, you’ll add 4 mLs of saline. Once the formula is prepared, apply it to the area where the fat-dissolving injections will be used, followed by the fat-dissolving injection. Do not mix them in one syringe.
Dissolving fillers with Liporase is easy and safe, but when should you consider using it? While some reasons have already been mentioned throughout the article, here’s a concise and comprehensive list of specific purposes for which Liporase can be used:
The biggest problem with the Liporase hyaluronidase injection (and any other hyaluronidase-based one) is that hyaluronidase can cause an immediate hypersensitivity reaction. Delayed hypersensitivity reactions can also happen but are rarer. Therefore, it’s important to conduct a skin test before proceeding with Liporase application. It should be noted that allergic reactions can’t be treated with antibiotics.
Liporase is approved by the Korean Ministry of Food and Drug Safety (MFDS), formerly known as the Korea Food & Drug Administration (KFDA). It doesn’t have FDA approval or a CA mark, but its substances are safe and commonly used in other products. Liporase ingredients are hyaluronidase and lactose hydrate.
Using Liporase presents a safe and efficient method for removing unwanted dermal fillers from the patient’s body. With its ability to selectively target synthetic hyaluronic acid, Liporase provides a reliable means to correct uneven filler distribution, address an unwanted appearance, manage filler migration, mitigate allergic reactions, and restore natural proportions by reducing excessive volume. Furthermore, its role in boosting the absorption of fat-dissolving injections ensures optimized outcomes in body contouring. By harnessing Liporase’s capabilities, medical professionals can ensure a smoother and safer treatment of their patients.
Liporase starts working after 24 to 48 hours.
Liprose works by breaking the bonding molecules that hold dermal fillers together.
You don’t mix them together; instead, you prepare and administer Liporase first to the desired area and then administer Lipo Lab or any other fat-reducing injection.
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