Business Hours: Monday-Friday 9AM-6PM EST
Brand:
GARDASIL®
Manufacturer:
MSD
Active Substance(s):
HPV PROTEINS
Strength:
0.5ml
Pack size:
1 x 0.5ml Vial, 1 x Pre-Filled Syringe
Each dose of Gardasil 9 is 0.5 mL. Administer Gardasil 9 as follows:
Age | Regimen | Schedule |
---|---|---|
9 through 14 years | 2-dose | 0, 6 to 12 months* |
3-dose | 0, 2, 6 months | |
15 through 45 years | 3-dose | 0, 2, 6 months |
*If the second dose is administered earlier than 5 months after the first dose, administer a third dose at least 4 months after the second dose.
GARDASIL 9 is a vaccine indicated in girls and women 9 through 45 years of age for the prevention of the following diseases:
GARDASIL 9 is indicated in boys and men 9 through 45 years of age for the prevention of the following diseases:
The oropharyngeal and head and neck cancer indication is approved under accelerated approval based on effectiveness in preventing HPV-related anogenital disease.
Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.
GARDASIL 9, Human Papillomavirus 9-valent Vaccine, Recombinant, is a non-infectious recombinant 9-valent vaccine prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, 18, 31, 33, 45, 52, and 58. The L1 proteins are produced by separate fermentations using recombinant Saccharomyces cerevisiae and self-assembled into VLPs. The fermentation process involves growth of S. cerevisiae on chemically-defined fermentation media which include vitamins, amino acids, mineral salts, and carbohydrates. The VLPs are released from the yeast cells by cell disruption and purified by a series of chemical and physical methods. The purified VLPs are adsorbed on preformed aluminum-containing adjuvant (Amorphous Aluminum Hydroxyphosphate Sulfate or AAHS). The 9-valent HPV VLP vaccine is a sterile liquid suspension that is prepared by combining the adsorbed VLPs of each HPV type and additional amounts of the aluminum-containing adjuvant and the final purification buffer.
Each dose of Gardasil 9 is 0.5 mL. Administer Gardasil 9 as follows:
Age | Regimen | Schedule |
---|---|---|
9 through 14 years | 2-dose | 0, 6 to 12 months* |
3-dose | 0, 2, 6 months | |
15 through 45 years | 3-dose | 0, 2, 6 months |
*If the second dose is administered earlier than 5 months after the first dose, administer a third dose at least 4 months after the second dose.
GARDASIL 9 is a vaccine indicated in girls and women 9 through 45 years of age for the prevention of the following diseases:
GARDASIL 9 is indicated in boys and men 9 through 45 years of age for the prevention of the following diseases:
The oropharyngeal and head and neck cancer indication is approved under accelerated approval based on effectiveness in preventing HPV-related anogenital disease.
Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.
GARDASIL 9, Human Papillomavirus 9-valent Vaccine, Recombinant, is a non-infectious recombinant 9-valent vaccine prepared from the purified virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, 18, 31, 33, 45, 52, and 58. The L1 proteins are produced by separate fermentations using recombinant Saccharomyces cerevisiae and self-assembled into VLPs. The fermentation process involves growth of S. cerevisiae on chemically-defined fermentation media which include vitamins, amino acids, mineral salts, and carbohydrates. The VLPs are released from the yeast cells by cell disruption and purified by a series of chemical and physical methods. The purified VLPs are adsorbed on preformed aluminum-containing adjuvant (Amorphous Aluminum Hydroxyphosphate Sulfate or AAHS). The 9-valent HPV VLP vaccine is a sterile liquid suspension that is prepared by combining the adsorbed VLPs of each HPV type and additional amounts of the aluminum-containing adjuvant and the final purification buffer.
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