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Entyvio (vedolizumab) is a prescription medicine used in adults to treat severe gastrointestinal conditions such as ulcerative colitis (UC) and Crohn's disease (CD). The medicine is designed to target the α4β7 integrin, playing a critical role in the pathogenesis of UC and CD by selectively modulating the gut's immune response without widespread immune suppression. Healthcare professionals can buy ENTYVIO to offer solutions and remission to patients who have not adequately responded to conventional therapies, including TNFα antagonists. However, it’s important to get the medicine through authorized channels to ensure patient’s safety.
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What Is ENTYVIO Used For?

Entyvio is an immunotherapy designed to treat moderate to severe ulcerative colitis (UC) and Crohn's disease (CD) in adults. It impedes the movement of white blood cells into the gut lining which helps reduce inflammation without suppressing the immune system.  It’s especially effective for patients who have not found relief with conventional therapy or TNFα antagonists.  When used regularly, Entyvio has been shown to induce and maintain remission and reduce the need for steroids in patients suffering from UC and CD. Clinics who wish to order ENTYVIO online can contact our sales team to get information on where to buy certified products. By targeting the α4β7 integrin, Entyvio operates at the cellular level to prevent the pathological interaction between white blood cells and the intestinal lining. Which gives it a more focused approach to managing these conditions. 

ENTYVIO Administration Technique

There are two ways Entyvio is administered, intravenously and subcutaneously. It’s important to note that there are specific infusion protocols that healthcare professionals must follow.  The initial intravenous dosing schedule begins with an infusion at 0, 2, and 6 weeks, followed by a maintenance dose every 8 weeks of therapy. Each infusion is delivered over a 30-minute period, during which the patient must be monitored for adverse reactions. It’s important to buy ENTYVIO online from authorized pharmaceutical providers to minimize any risks. Pre-medication is generally not required but should be considered if there are any infusion-related reactions in the patient’s medical history.  To prepare for the infusion, Entyvio should be diluted in sterile 0.9% Sodium Chloride Injection, USP, to a final concentration of 300 mg in 250 mL. Doctors should visually inspect the solution to check for any discoloration before administration. After the infusion, all patients should be observed for signs of allergic or infusion-related reactions. If there is a severe reaction, the infusion must be stopped and appropriate medical help should be given. Patients can also administer medicine at home using the ENTYVIO Pen for subcutaneous administration. It can be administered in three different areas of the body: in the stomach or thigh, or in the back of the arms (by a caregiver only).

ENTYVIO Side Effects

Healthcare professionals who choose to buy ENTYVIO for their practice are well aware of all the side effects.  Entyvio is effective in managing these conditions but has common side effects which include headache, joint pain, nausea, fever, fatigue, and respiratory infections. These reactions are generally manageable and often do not necessitate discontinuation of therapy. However, there are more serious concerns about this medicine, such as an increased risk of serious infections (e.g., tuberculosis, sepsis) and infusion-related reactions. Patients should be carefully monitored before and after infusion at all times.  Additionally, some patients report experiencing progressive multifocal leukoencephalopathy (PML). It’s a rare but serious brain infection, however, the direct association with Entyvio is not clear.  Clinics should buy ENTYVIO wholesale only from authorized distributors to minimize any unwanted reactions.

ENTYVIO vs. Competition

Besides Entyvio, there are other medications doctors can use to treat conditions such as ulcerative colitis (UC) and Crohn's disease (CD). Infliximab (Remicade) and Adalimumab (Humira) are the two main competitor brands. Infliximab (Remicade) is a TNFα inhibitor that is administered via infusion. It’s effective in treating both UC and CD. However, it may lead to systemic immunosuppression which increases the risk of serious infections. Healthcare professionals who wish to buy ENTYVIO online for their practice should be aware of all these distinctions. Adalimumab (Humira) is another TNFα inhibitor, which is administered through subcutaneous injections. It can also be administered at home which makes it more convenient for patients who prefer that option and is suitable for children. But it also carries similar risks of systemic immunosuppression. Unlike TNFα inhibitors mentioned above, Entyvio specifically targets the gut, minimizing systemic immunosuppressive effects. It has a lower reported incidence of serious infections compared to systemic immunosuppressants.

Where Can I Buy ENTYVIO?

Clinics who wish to incorporate Entyvio into their treatment regimens for moderate to severe ulcerative colitis (UC) and Crohn's disease (CD) should always purchase from reliable sources.  Entyvio is available through a network of authorized distributors and pharmacies and our team can help you find and purchase the medicine for your practice.



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